College of Environmental Science and Engineering, Tianjin University, Tianjin, 300071, China.
Environ Sci Pollut Res Int. 2015 Jan;22(2):1215-9. doi: 10.1007/s11356-014-3432-4. Epub 2014 Aug 17.
With the generalized linear model and natural splines (ns), we examined the association between outdoor air pollutants and daily morbidity for diabetes and liver disease stratified by sexes and ages based on 4 years of daily data (2008-2011) in Tianjin, China. Season effects of air pollutants including particulate matter (PM), sulfur dioxide (SO2), and nitrogen dioxide (NO2) were also investigated. An increase of 10 μg/m(3) in a 2-day average concentrations of particulate matter with diameters of 10 μm or less (PM10), SO2, and NO2 corresponds to increases in diabetes morbidity of 0.39 % (95 % confidence interval (CI), -0.42-1.12), 0.15 % (95 % CI, -0.25-0.54), and 1.22 % (95 % CI, 0.51-2.96), respectively. As for liver morbidity, the increases were -0.84 % (95 % CI, -2.33-0.62), 0.90 % (95 % CI, 0.50-1.74), and 1.10 % (95 % CI, -2.58-4.78), respectively. The effects were stronger in the cool season than those in the warm season; females and the elderly were generally more vulnerable to outdoor air pollution. This study possesses scientific implications and instructional significance for local environmental standards and medical policymaking.
我们采用广义线性模型和自然样条（ns），根据中国天津四年（2008-2011 年）的每日数据，对糖尿病和肝脏疾病的男女和年龄分层，考察了室外空气污染物与每日发病率之间的关联。我们还研究了空气污染物（包括颗粒物（PM）、二氧化硫（SO2）和二氧化氮（NO2））的季节效应。PM10、SO2 和 NO2 的两日平均浓度每增加 10μg/m3，糖尿病发病率分别增加 0.39%（95%置信区间（CI）：-0.42-1.12）、0.15%（95%CI：-0.25-0.54）和 1.22%（95%CI：0.51-2.96）。对于肝脏疾病，发病率分别下降 0.84%（95%CI：-2.33-0.62）、0.90%（95%CI：0.50-1.74）和 1.10%（95%CI：-2.58-4.78）。在凉爽季节的影响大于温暖季节；女性和老年人通常更容易受到室外空气污染的影响。本研究对当地环境标准和医疗政策制定具有科学意义和教学意义。
