Briesen Sebastian, Roberts Helen, Finger Robert P
MVZ Jung-Stilling Hospital , Siegen , Germany .
Ophthalmic Epidemiol. 2014 Oct;21(5):297-306. doi: 10.3109/09286586.2014.950281. Epub 2014 Aug 18.
To assess the impact of visual impairment (VI) on utility values in Sub-Saharan Africa and compare findings with other studies from low- and high-income countries.
Patients with normal vision and various levels of VI were recruited from a secondary eye clinic in rural Kenya and interviewed using time trade-off (TTO). VI was classified using the World Health Organization definition of (normal vision, visual acuity ≥20/60, VI 20/80-20/200, severe VI 20/240-20/400, and blindness <20/400).
Mean age of the total sample (N = 303) was 50.3 years (standard deviation, SD, ±18.17 years), and 51.5% of patients were male. Most were small-scale farmers and illiteracy was high at 40%. Mean TTO scores per group were: normal vision 0.93 (SD ± 0.10), VI 0.88 (SD ± 0.14), severe VI 0.86 (SD ± 0.13), blindness 0.73 (SD ± 0.17; p ≤ 0.001). Lower TTO scores were independently associated with worse visual acuity (p ≤ 0.001), longer duration of disease (p ≤ 0.001) and illiteracy (p = 0.011), but not with cause of VI, age, sex, marital status, socioeconomic status, or systemic comorbidities in multivariate analyses. Overall, TTO scores were considerably higher than those reported from high-income countries at similar levels of VI.
In this rural African population, duration and extent of vision loss, rather than cause, socioeconomic factors and comorbidities affected vision-related quality of life. Our findings underline the importance of providing sight-restoring treatment as timely as possible and the necessity of enhancing rehabilitation efforts for those with non-curable eye diseases.
评估视力损害(VI)对撒哈拉以南非洲地区效用值的影响,并将研究结果与来自低收入和高收入国家的其他研究进行比较。
从肯尼亚农村的一家二级眼科诊所招募视力正常和不同程度视力损害的患者,并采用时间权衡法(TTO)进行访谈。根据世界卫生组织的定义对视力损害进行分类(正常视力,视力≥20/60;视力损害20/80 - 20/200;严重视力损害20/240 - 20/400;失明<20/400)。
总样本(N = 303)的平均年龄为50.3岁(标准差,SD,±18.17岁),51.5%的患者为男性。大多数是小规模农民,文盲率高达40%。每组的平均TTO得分分别为:正常视力0.93(SD±0.10),视力损害0.88(SD±0.14),严重视力损害0.86(SD±0.13),失明0.73(SD±0.17;p≤0.001)。在多变量分析中,较低的TTO得分与较差的视力(p≤0.001)、较长的病程(p≤0.001)和文盲(p = 0.011)独立相关,但与视力损害的原因、年龄、性别、婚姻状况、社会经济地位或全身合并症无关。总体而言,在类似视力损害水平下,TTO得分远高于高收入国家报告的得分。
在这个非洲农村人群中,视力丧失的持续时间和程度而非原因、社会经济因素和合并症影响了与视力相关的生活质量。我们的研究结果强调了尽早提供恢复视力治疗的重要性以及加强对不可治愈眼病患者康复努力的必要性。