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在埃塞俄比亚东北部 Boru Meda 综合医院就诊的青光眼患者的生活质量及其相关因素。

Quality of life and associated factors among patients with glaucoma attending at Boru Meda General Hospital, Northeast Ethiopia.

机构信息

Department of Adult Health Nursing, Borumeda General Hospital, Dessie, Ethiopia.

Clinical Pharmacy Unit, Department of Pharmacy, College of Health Sciences, Woldia University, P.O. Box 400, Woldia, Ethiopia.

出版信息

Sci Rep. 2024 Nov 22;14(1):28969. doi: 10.1038/s41598-024-77422-6.

DOI:10.1038/s41598-024-77422-6
PMID:39578501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11584743/
Abstract

Glaucoma significantly impacts the well-being of millions of people worldwide and contributes to a decline in quality of life. Therefore, this study aimed to evaluate quality of life and identify influencing factors among glaucoma patients receiving care at Boru Meda General Hospital in Northeast Ethiopia in 2022. A hospital-based cross-sectional study was conducted at Boru Meda General Hospital from July 10 to September 10, 2022. A total of 432 glaucoma patients were selected through a simple random sampling technique. The participants were interviewed via a structured questionnaire, including the modified Glaucoma Quality of Life-15 tool. The data collected were processed by cleaning, coding, and entering into EPi-data version 4.6 and then analysed via SPSS version 26. Variables with a p value less than 0.05 at the 95% confidence interval were considered statistically significant. A total of 417 participants participated in the study, resulting in a response rate of 96.4%. Among them, 187 individuals, accounting for 44.2% (95% CI 39.8-49.9%), reported having poor quality of life. Factors such as being diagnosed for more than 6 years, residing in rural areas, having other ocular diseases, having bilateral glaucoma, receiving treatment for 1-5 years, experiencing moderate anxiety, and facing moderate depression were significantly associated with poor quality of life, with adjusted odds ratios ranging from 2.555 to 8.035. Approximately half of the participants experienced a diminished quality of life, and significant associations were found with rural residence, time since diagnosis, treatment duration, the presence of other ocular conditions, bilateral glaucoma, and levels of anxiety and depression. The implementation of community-based glaucoma screening initiatives aimed at early identification and treatment, particularly those focused on rural communities and individuals with bilateral glaucoma, is crucial.

摘要

青光眼严重影响了全球数百万人的生活福祉,并导致生活质量下降。因此,本研究旨在评估 2022 年在埃塞俄比亚东北部 Boru Meda 综合医院接受治疗的青光眼患者的生活质量,并确定影响生活质量的因素。本研究采用医院横断面研究设计,于 2022 年 7 月 10 日至 9 月 10 日在 Boru Meda 综合医院进行。采用简单随机抽样技术抽取了 432 名青光眼患者。通过结构式问卷对参与者进行访谈,问卷包括改良后的 Glaucoma Quality of Life-15 工具。收集的数据经过清理、编码和录入 EPiData 版本 4.6 后,使用 SPSS 版本 26 进行分析。在 95%置信区间,p 值小于 0.05 的变量被认为具有统计学意义。共有 417 名参与者参与了研究,应答率为 96.4%。其中,187 人(44.2%[95%CI 39.8-49.9%])报告生活质量较差。诊断时间超过 6 年、居住在农村地区、患有其他眼部疾病、患有双侧青光眼、治疗 1-5 年、中度焦虑和中度抑郁与生活质量较差显著相关,调整后的比值比范围为 2.555-8.035。大约一半的参与者生活质量下降,与农村居住、诊断后时间、治疗持续时间、其他眼部疾病、双侧青光眼以及焦虑和抑郁水平显著相关。实施以社区为基础的青光眼筛查计划,旨在早期发现和治疗青光眼,特别是针对农村社区和双侧青光眼患者,这一点至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2093/11584743/5a42d1db48f8/41598_2024_77422_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2093/11584743/5a42d1db48f8/41598_2024_77422_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2093/11584743/5a42d1db48f8/41598_2024_77422_Fig1_HTML.jpg

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