Gupta Aditi, Gopal Lingam, Sen Parveen, Ratra Dhanashree, Rao Chetan
Department of Vitreoretinal Services, Shri Bhagwan Mahavir, 18, College Road, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Department of Ophthalmology, National University Hospital, 5 Lower Kent Ridge Road, Singapore.
Oman J Ophthalmol. 2014 May;7(2):78-80. doi: 10.4103/0974-620X.137162.
Though choroidal osteoma is a rare benign tumor, associated choroidal neovascularization (CNV) can be a cause of severe visual loss. A nine-year-old boy presented with one-month history of decreased vision in left eye. Upon a complete ophthalmologic examination, including fundus fluorescein angiography and optical coherence tomography, he was diagnosed with choroidal osteoma-related subfoveal CNV in the left eye. The CNV was associated with subretinal hemorrhage, subretinal fluid, and cystoid macular edema. Owing to the young age and subfoveal localization of the CNV, intravitreal ranibizumab injection was performed on this patient after a detailed discussion with the parents of its safety profile. No local or systemic complications were noted. No recurrence of CNV lesion was noted during 30 months of follow-up, and the vision was maintained. This report shows the favorable outcome of intravitreal injection of ranibizumab in choroidal osteoma-related CNV in a child.
尽管脉络膜骨瘤是一种罕见的良性肿瘤，但相关的脉络膜新生血管（CNV）可能导致严重的视力丧失。一名9岁男孩因左眼视力下降1个月前来就诊。经过包括眼底荧光血管造影和光学相干断层扫描在内的全面眼科检查，他被诊断为左眼脉络膜骨瘤相关的黄斑下CNV。该CNV伴有视网膜下出血、视网膜下液和黄斑囊样水肿。由于患者年龄小且CNV位于黄斑下，在与患儿家长详细讨论了雷珠单抗玻璃体腔注射的安全性后，对该患者进行了注射。未发现局部或全身并发症。在30个月的随访中未发现CNV病变复发，视力得以维持。本报告显示了玻璃体腔注射雷珠单抗治疗儿童脉络膜骨瘤相关CNV的良好效果。
