Department of Statistics and O. R., Public University of Navarre, Campus de Arrosadia, Pamplona, Navarre, Spain.
Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Popul Health Metr. 2014 Jul 10;12:17. doi: 10.1186/1478-7954-12-17. eCollection 2014.
In this paper, space-time patterns of colorectal cancer (CRC) mortality risks are studied by sex and age group (50-69, ≥70) in Spanish provinces during the period 1975-2008. Space-time conditional autoregressive models are used to perform the statistical analyses. A pronounced increase in mortality risk has been observed in males for both age-groups. For males between 50 and 69 years of age, trends seem to stabilize from 2001 onward. In females, trends reflect a more stable pattern during the period in both age groups. However, for the 50-69 years group, risks take an upward trend in the period 2006-2008 after the slight decline observed in the second half of the period. This study offers interesting information regarding CRC mortality distribution among different Spanish provinces that could be used to improve prevention policies and resource allocation in different regions.
本文研究了 1975 年至 2008 年间西班牙各省份按性别和年龄组（50-69 岁，≥70 岁）划分的结直肠癌（CRC）死亡率的时空模式。采用时空条件自回归模型进行统计分析。结果显示，50-69 岁和≥70 岁男性的死亡率均呈明显上升趋势。50-69 岁的男性自 2001 年以来，趋势似乎趋于稳定。在女性中，两个年龄组的死亡率在整个研究期间都呈现出更为稳定的趋势。然而，50-69 岁年龄组在该期间的后半段出现轻微下降后，于 2006-2008 年期间呈现上升趋势。本研究为不同西班牙省份的 CRC 死亡率分布提供了有趣的信息，有助于改善不同地区的预防政策和资源分配。
