人类原癌基因c-yes-1在18号染色体q21.3带的区域定位。
Regional mapping of the human proto-oncogene c-yes-1 to chromosome 18 at band q21.3.
作者信息
Yoshida M C, Sasaki M, Mise K, Semba K, Nishizawa M, Yamamoto T, Toyoshima K
出版信息
Jpn J Cancer Res. 1985 Jul;76(7):559-62.
PMID:3928550
Abstract
Human proto-oncogene c-yes-1 homologous to the viral oncogene (v-yes) of an avian Y73 sarcoma virus was mapped to region q21.3 of chromosome 18 by in situ hybridization. This finding confirmed and more rigidly substantiated the previous assignment which was based on analyses of human X mouse somatic cell hybrids and Southern blots.
摘要
通过原位杂交技术，将与禽Y73肉瘤病毒的病毒癌基因（v-yes）同源的人类原癌基因c-yes-1定位到18号染色体的q21.3区域。这一发现证实并更有力地支持了先前基于人类X小鼠体细胞杂种分析和Southern印迹法所做的定位。
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