Gustafsson K, Svensson T, Uggla A
Zentralbl Veterinarmed A. 1989 Oct;36(8):631-7. doi: 10.1111/j.1439-0442.1989.tb00774.x.
At routine post mortem examinations performed at the National Veterinary Institute (NVI), Uppsala, Sweden, during November 1983-May 1984, a syndrome principally characterized by an acute hepatosis was found in 85 out of 177 brown hares (Lepus europaeus P.). The hepatic lesions consisted of periportal or extensive necrosis and haemorrhages. Concomitant changes in other organs were tubular necrosis in the kidneys, acute catarrhal enteritis, severe congestion, oedema and haemorrhages of the lungs, hyperemia of the spleen, and in some cases jaundice. A supplementary retrospective study of liver sections from another 388 brown hares and 202 mountain hares (Lepus timidus L.), autopsied at NVI during 1980-1985, revealed 35 additional cases of the acute hepatosis, 32 being in brown hares and 3 in mountain hares. The histopathology of the liver lesions may suggest a toxic etiology.
1983年11月至1984年5月期间,在瑞典乌普萨拉国家兽医研究所(NVI)进行的常规尸检中,177只棕色野兔(欧洲野兔)中有85只出现了一种主要以急性肝病为特征的综合征。肝脏病变包括门周或广泛性坏死及出血。其他器官的伴随变化有肾脏的肾小管坏死、急性卡他性肠炎、肺部严重充血、水肿和出血、脾脏充血,有些病例还出现黄疸。对1980 - 1985年期间在NVI进行尸检的另外388只棕色野兔和202只山地野兔(Lepus timidus L.)的肝脏切片进行的补充回顾性研究发现,又有35例急性肝病病例,其中32例为棕色野兔,3例为山地野兔。肝脏病变的组织病理学可能提示有毒性病因。