McCann M F, Moggia A V, Higgins J E, Potts M, Becker C
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill.
Contraception. 1989 Dec;40(6):635-48. doi: 10.1016/0010-7824(89)90068-1.
This study was a non-randomized clinical trial which compared the breast-feeding experience of 250 Argentine women taking levonorgestrel 0.03 mg daily (begun one week after delivery) with that of 250 women using non-hormonal contraceptives. Weight gain of unsupplemented infants, the most important of the several criteria used to assess breast-feeding performance, was similar for the two contraceptive groups. Levonorgestrel users began supplementary feeding of their infants significantly later than did non-hormonal users; levonorgestrel users were also somewhat less likely to discontinue breast-feeding during the study period. The two contraceptive groups were similar with regard to several other measures of breast-feeding performance: growth of all infants (regardless of supplementation), patterns of contraceptive discontinuation, mothers' subjective impressions of breast-milk sufficiency, and comparison of supplementation initiation with previous experience.
本研究为一项非随机临床试验，比较了250名每天服用0.03毫克左炔诺孕酮（产后一周开始服用）的阿根廷女性与250名使用非激素避孕药的女性的母乳喂养经历。未添加辅食婴儿的体重增加情况是评估母乳喂养表现的几个重要标准之一，两个避孕组的情况相似。服用左炔诺孕酮的女性开始给婴儿添加辅食的时间明显晚于使用非激素避孕药的女性；在研究期间，服用左炔诺孕酮的女性停止母乳喂养的可能性也略低。在母乳喂养表现的其他几项指标上，两个避孕组相似：所有婴儿的生长情况（无论是否添加辅食）、避孕药停用模式、母亲对母乳充足性的主观印象，以及与以往经历相比添加辅食开始时间的情况。
