Braw-Tal R, Gootwine E
Institute of Animal Science, A.R.O., Volcani Center, Bet Dagan, Israel.
J Reprod Fertil. 1989 Sep;87(1):73-80. doi: 10.1530/jrf.0.0870073.
Booroola-Awassi ewe lambs were heterozygous (F+) for a major gene F, influencing their ovulation rate, while Awassi lambs were non-carriers (++). Basal plasma FSH concentration (mean +/- s.e.m.) in Booroola-Awassi ewe lambs at 4 weeks of age was significantly higher than in Awassi lambs of the same age (5.06 +/- 0.60 and 2.04 +/- 0.32 ng/ml respectively; P less than 0.001). After GnRH administration, FSH increased from 3.89 +/- 1.10 to 10.58 +/- 1.30 ng/ml in Booroola-Awassi (N = 6) and from 1.87 +/- 0.29 to 4.64 +/- 0.33 ng/ml in Awassi (N = 6) ewe lambs (P less than 0.05). Ovariectomy caused an increase in plasma FSH in Booroola-Awassi (N = 4) and Awassi (N = 4) ewe lambs. At 1 week after ovariectomy plasma FSH increased from 5.96 +/- 1.02 to 7.06 +/- 1.05 ng/ml in F+ and from 1.67 +/- 1.06 to 5.21 +/- 0.66 ng/ml in ++ ewe lambs, suggesting a stronger negative feed-back effect exerted by the ovaries of Awassi lambs. At 15 weeks after ovariectomy FSH values were similar in Booroola-Awassi (18.28 +/- 1.96 ng/ml) and Awassi (16.07 +/- 0.70 ng/ml) lambs. Although the overall pattern of pituitary response to ovariectomy was similar in the F+ and ++ ewe lambs, Booroola-Awassi lambs had small ovaries (132.5 +/- 24.9 mg) and follicular development did not proceed beyond the preantral stage in 3/4 animals, and Awassi lambs had large ovaries (600.0 +/- 233.9 mg) (P less than 0.05) with many preantral and antral follicles.(ABSTRACT TRUNCATED AT 250 WORDS)
波拉-阿瓦西母羊羔羊对于影响排卵率的主基因F呈杂合状态（F+），而阿瓦西羔羊则是非携带者（++）。4周龄的波拉-阿瓦西母羊羔羊的基础血浆促卵泡素（FSH）浓度（平均值±标准误）显著高于同龄的阿瓦西羔羊（分别为5.06±0.60和2.04±0.32纳克/毫升；P<0.001）。给予促性腺激素释放激素（GnRH）后，波拉-阿瓦西（N=6）母羊羔羊的FSH从3.89±1.10纳克/毫升增至10.58±1.30纳克/毫升，阿瓦西（N=6）母羊羔羊的FSH从1.87±0.29纳克/毫升增至4.64±0.33纳克/毫升（P<0.05）。卵巢切除术导致波拉-阿瓦西（N=4）和阿瓦西（N=4）母羊羔羊的血浆FSH升高。卵巢切除术后1周，F+母羊羔羊的血浆FSH从5.96±1.02纳克/毫升增至7.06±1.05纳克/毫升，++母羊羔羊的血浆FSH从1.67±1.06纳克/毫升增至5.21±0.66纳克/毫升，这表明阿瓦西羔羊的卵巢产生的负反馈作用更强。卵巢切除术后15周，波拉-阿瓦西（18.28±1.96纳克/毫升）和阿瓦西（16.07±0.70纳克/毫升）羔羊的FSH值相似。尽管F+和++母羊羔羊垂体对卵巢切除术的总体反应模式相似，但波拉-阿瓦西羔羊的卵巢较小（132.5±24.9毫克），3/4的动物卵泡发育未超过窦前阶段，而阿瓦西羔羊的卵巢较大（600.0±233.9毫克）（P<0.05），有许多窦前和窦状卵泡。（摘要截断于250字）
