Montgomery G W, Scott I C, Littlejohn R P, Davis G H, Peterson A J
Invermay Agricultural Centre, Mosgiel, New Zealand.
Reprod Fertil Dev. 1989;1(4):299-307. doi: 10.1071/rd9890299.
Concentrations of FSH were measured in new-born lambs in Booroola Merino x Romney and Booroola Merino flocks where the Booroola F gene was segregating, and in progeny from sires of a prolific strain of Romney sheep. FSH concentrations increased with age and liveweight in Booroola Merino x Romney ewe lambs to reach peak concentrations at 4-6 weeks of age. Significantly higher mean concentrations were recorded in ewe lambs homozygous for the Booroola gene (FF) compared with non-carrier (+ +) ewe lambs. Concentrations in heterozygous (F+) ewe lambs were intermediate. Maximum differences between the genotypes were recorded at 6 weeks of age. Significantly higher FSH concentrations were also recorded in F-gene-carrier female lambs when compared to non-carriers in two other flocks. FSH concentrations remained low in ram lambs up to 12 weeks of age, and there were no differences between Booroola genotypes. The progeny of one ram from the prolific Romney family had high ovulation rates at 18 months of age. The progeny of other related rams showed no increase in ovulation rates at 18 months of age. Concentrations of FSH in the high-ovulation-rate progeny at 3 and 5 weeks of age did not differ from those in the low-ovulation-rate progeny, but were lower than those in the progeny of an FF Booroola Merino x Romney ram. These results support the hypothesis that neonatal concentrations of FSH are higher in lambs carrying the Booroola F gene, but not in all prolific strains since high FSH concentrations were not recorded in daughters from a prolific Romney flock.(ABSTRACT TRUNCATED AT 250 WORDS)
在布鲁拉美利奴羊与罗姆尼羊杂交且布鲁拉F基因发生分离的羊群，以及多产罗姆尼羊品系公羊的后代中，对新生羔羊的促卵泡素（FSH）浓度进行了测定。在布鲁拉美利奴羊与罗姆尼羊杂交的母羊羔中，FSH浓度随年龄和体重增加，在4 - 6周龄时达到峰值浓度。与非携带者（++）母羊羔相比，布鲁拉基因纯合（FF）的母羊羔记录到显著更高的平均浓度。杂合（F+）母羊羔的浓度处于中间水平。在6周龄时记录到基因型之间的最大差异。在另外两个羊群中，与非携带者相比，F基因携带者母羊羔的FSH浓度也显著更高。在12周龄之前，公羊羔的FSH浓度一直较低，布鲁拉基因型之间没有差异差异。来自多产罗姆尼家族的一只公羊的后代在18月龄时排卵率较高。其他相关公羊的后代在18月龄时排卵率没有增加。高排卵率后代在3周和5周龄时的FSH浓度与低排卵率后代没有差异，但低于FF布鲁拉美利奴羊与罗姆尼羊杂交公羊的后代。这些结果支持了这样的假设，即携带布鲁拉F基因羔羊的新生儿FSH浓度较高，但并非所有多产品系都是如此，因为在一个多产罗姆尼羊群的后代中未记录到高FSH浓度。（摘要截短至250字）
