van Beljouw Ilse M J, Laurant Miranda G H, Heerings Marjolijn, Stek Max L, van Marwijk Harm W J, van Exel Eric
Department of General Practice and Elderly Care Medicine, VU University Medical Center and EMGO + Institute for Health and Care Research, van der Boechorststraat, Amsterdam, 1081 BT, The Netherlands.
Implement Sci. 2014 Aug 28;9:107. doi: 10.1186/s13012-014-0107-y.
Depressive symptoms are highly prevalent in old age, but they remain mostly untreated. Several clinical trials have shown promising results in preventing or reducing depressive symptoms. However, it is not clear how robust these effects are in the real world of day-to-day care. Therefore, we have implemented the 'Lust for Life' programme, which significantly reduced depressive symptoms in community-dwelling older adults in the first three months after implementation. This mixed-methods study was conducted alongside the trial to develop a contextualised understanding of factors affecting the implementation.
A total of 263 persons of 65 years and older with depressive symptoms were recruited from 18 general practices and home care organizations in the Netherlands. We used qualitative data (in-depth interviews and focus group discussions with participants with depressive symptoms and healthcare professionals) as well as quantitative data (longitudinal data on the severity of depressive symptoms) to explore hindering and facilitating factors to the implementation of the 'Lust for Life' programme.
The uptake of the routine screening was poor and imposed significant burdens on participants and healthcare professionals, and drop-out rates were high. Participants' perceived mental problems and need for care played a key role in their decision to participate in the programme and to step up to consequent interventions. Older people preferred interventions that focused on interpersonal contact. The programme was only effective when delivered by mental healthcare nurses, compared to home care nurses with limited experience in providing mental healthcare.
The intervention programme was effective in reducing depressive symptoms, and valuable lessons can be learned from this implementation trial. Given the low uptake and high investment, we advise against routine screening for depressive symptoms in general healthcare. Further, agreement between the participant and healthcare professional on perceived need for care and intervention is vital. Rather than providing a stepped care intervention programme, we showed that offering only one single preference-led intervention is effective. Lastly, since the provision of the interventions seems to ask for specific skills and experiences, it might require mental healthcare nurses to offer the programme.
Dutch trial register NTR2241.
抑郁症状在老年人中极为普遍,但大多未得到治疗。多项临床试验在预防或减轻抑郁症状方面显示出了有前景的结果。然而,在日常护理的实际环境中这些效果的稳健程度尚不清楚。因此,我们实施了“热爱生活”项目,该项目在实施后的头三个月显著减轻了社区居家老年人的抑郁症状。这项混合方法研究与试验同步进行,以深入了解影响实施的因素。
从荷兰的18家全科诊所和家庭护理机构招募了总共263名65岁及以上有抑郁症状的人。我们使用定性数据(对有抑郁症状的参与者和医疗保健专业人员进行深入访谈和焦点小组讨论)以及定量数据(抑郁症状严重程度的纵向数据)来探索阻碍和促进“热爱生活”项目实施的因素。
常规筛查的接受度很低,给参与者和医疗保健专业人员带来了沉重负担,且退出率很高。参与者感知到的心理问题和护理需求在他们决定参与该项目并接受后续干预中起关键作用。老年人更喜欢侧重于人际接触的干预措施。与在提供心理保健方面经验有限的家庭护理护士相比,该项目仅在由心理保健护士实施时才有效。
干预项目在减轻抑郁症状方面是有效的,并且可以从该实施试验中吸取宝贵经验教训。鉴于接受度低和投入高,我们建议在普通医疗保健中不要对抑郁症状进行常规筛查。此外,参与者和医疗保健专业人员就感知到的护理和干预需求达成一致至关重要。我们发现,与其提供逐步护理干预项目,仅提供一种单一的基于偏好的干预措施就有效。最后,由于提供干预措施似乎需要特定的技能和经验,可能需要心理保健护士来实施该项目。
荷兰试验注册编号NTR2241。