Sander James C, Bilgutay Aylin N, Stanasel Irina, Koh Chester J, Janzen Nicolette, Gonzales Edmond T, Roth David R, Seth Abhishek
Scott Department of Urology, Baylor College of Medicine (ANB) and Texas Children's Hospital, Houston, Texas.
Scott Department of Urology, Baylor College of Medicine (ANB) and Texas Children's Hospital, Houston, Texas.
J Urol. 2015 Feb;193(2):662-6. doi: 10.1016/j.juro.2014.08.095. Epub 2014 Aug 26.
We assessed outcomes in children with ureterocele after transurethral incision at our institution between 2001 and 2014, focusing on end points of vesicoureteral reflux, improvement of hydronephrosis and need for second surgery.
We performed chart reviews of 83 patients, collecting information including age at transurethral incision, gender, renal anatomy, ureterocele location, indication for transurethral incision, and preincision and postincision vesicoureteral reflux and hydronephrosis status. Patients were divided into those with single system and duplex system ureteroceles, and intravesical and extravesical location for analysis. Statistical evaluations were performed with the Wilcoxon rank test and Fisher exact test.
Transurethral incision was performed at a mean age of 34.2 months in patients with single system ureterocele and 8.9 months in those with duplex system ureterocele (p <0.0001). Cure rates (improvement of hydronephrosis and absence of vesicoureteral reflux) were 55.6% in patients with single system ureterocele and 14.9% in those with duplex system ureterocele (p = 0.0031). Rates of de novo reflux into the ureterocele moiety were 27.8% for patients with single system ureterocele and 56.2% for those with duplex system ureterocele (p = 0.0773). Patients with single system ureterocele required significantly fewer second surgeries (3.8%) than those with duplex system ureterocele (73.7%, p <0.0001).
Patients with single system ureterocele may benefit from endoscopic incision. Transurethral incision was definitive in all such patients except 1 in our study. Although most patients with duplex system ureterocele will need a second operation, transurethral incision remains of value in this population in instances of sepsis or bladder outlet obstruction, or to facilitate planned reconstruction when the child is older.
我们评估了2001年至2014年间在本机构接受经尿道切开术的输尿管囊肿患儿的治疗结果,重点关注膀胱输尿管反流、肾积水改善情况以及二次手术需求等终点指标。
我们对83例患者进行了病历回顾,收集了经尿道切开术时的年龄、性别、肾脏解剖结构、输尿管囊肿位置、经尿道切开术的指征以及切开术前和术后的膀胱输尿管反流及肾积水状况等信息。患者被分为单系统和重复系统输尿管囊肿,以及膀胱内和膀胱外位置进行分析。采用Wilcoxon秩和检验和Fisher精确检验进行统计学评估。
单系统输尿管囊肿患者经尿道切开术的平均年龄为34.2个月,重复系统输尿管囊肿患者为8.9个月(p<0.0001)。单系统输尿管囊肿患者的治愈率(肾积水改善且无膀胱输尿管反流)为55.6%,重复系统输尿管囊肿患者为14.9%(p = 0.0031)。单系统输尿管囊肿患者输尿管囊肿部分新发反流率为27.8%,重复系统输尿管囊肿患者为56.2%(p = 0.0773)。单系统输尿管囊肿患者需要二次手术的比例(3.8%)显著低于重复系统输尿管囊肿患者(73.7%,p<0.0001)。
单系统输尿管囊肿患者可能从内镜下切开术中获益。在我们的研究中,除1例患者外,经尿道切开术对所有此类患者都是决定性的。虽然大多数重复系统输尿管囊肿患者需要二次手术,但经尿道切开术在该人群中对于败血症或膀胱出口梗阻的情况,或在患儿长大后便于进行计划性重建时仍具有价值。