Singh G R, Malathi K E, Kasliwal R R, Ommar A, Padmavati S, Ramji S
Indian Pediatr. 1989 Sep;26(9):875-81.
Forty-six malnourished children between 3-48 mo with varying grades of malnutrition (PEM) were evaluated for left ventricular function by echocardiography. None of these children had any pre-existing cardiac disease, chronic illness or significant anemia. Children with Grades III and IV PEM had significantly smaller cardiac chamber size and ventricular wall thickness as compared to normally nourished children. Cardiac output as well as other indices of left ventricular function (percentage fractional shortening, mean rate of circumferential fibre shortening and ejection fraction) were also significantly decreased in severe PEM. The atrophic PEM heart does appear to show left ventricular dysfunction in moderately severe malnutrition.
通过超声心动图对46名年龄在3至48个月之间、患有不同程度营养不良(蛋白质-能量营养不良,PEM)的儿童进行左心室功能评估。这些儿童均无既往心脏病、慢性病或严重贫血。与营养正常的儿童相比,III级和IV级PEM患儿的心脏腔室大小和心室壁厚度明显更小。严重PEM患儿的心输出量以及左心室功能的其他指标(缩短分数百分比、平均圆周纤维缩短率和射血分数)也显著降低。在中度严重营养不良的情况下,萎缩性PEM心脏似乎确实表现出左心室功能障碍。