de Oliveira Alessandro, Cocate Paula G, Hermsdorff Helen Hermana M, Bressan Josefina, de Silva Mateus Freitas, Rodrigues Joel Alves, Natali Antônio José
Department of Nutrition and Health, Universidade Federal de Viçosa, Av, PH Rolfs, s/n, Viçosa, Minas Gerais 36570-000, Brazil.
Lipids Health Dis. 2014 Sep 1;13:141. doi: 10.1186/1476-511X-13-141.
Low-cost practical and reliable tools to evaluated obesity-related cardiometabolic diseases are of clinical practice and public heath relevance worldwide. The aims of this cross-sectional study were to determine the anatomical point of waist circumference that best identify overweight, obesity and central obesity in Southeast Brazilian middle-aged men and to test the relationships of its cutoff points with metabolic syndrome (MetS), insulin resistance (IR) and cardiometabolic risk factors.
Three hundred men [age: 51 (47-54)] underwent anthropometric, body composition, clinical, sociodemographic and blood plasma biochemical evaluations.
The umbilical line circumference (WCUL) was the best predictor for overweight (total body fat ≥ 20%; cutoff point: 88.8 cm), obesity (total body fat ≥ 25%; cutoff point: 93.4 cm) and central obesity (abdominal area fat ≥ 34.6%; cutoff point: 95.6 cm) as measured by dual beam X-ray absorptiometry. Subjects with WCUL ≥ 88.8 cm or ≥ 93.4 cm showed significantly higher values for MetS, IR and cardiometabolic risk factors (i.e. glucose and lipid profiles, blood pressure). The occurrence of WCUL ≥ 88.8 cm was positively associated (p <0.01) with the prevalence of MetS and cardiometabolic risk factors and increased the central obesity prevalence by 19.3% while that of WCUL ≥ 93.4 cm was associated with the prevalence of MetS, IR and cardiometabolic risk factors.
WCUL measure seems to be the best predictor for overweight, obesity and central obesity in urban residents Southeast Brazilian middle-aged men; and the WCUL cutoff point (88.8 cm) is significantly associated with MetS, IR and cardiometabolic risk factors in the studied population.
低成本、实用且可靠的评估肥胖相关心脏代谢疾病的工具在全球临床实践和公共卫生领域具有重要意义。这项横断面研究的目的是确定巴西东南部中年男性中最能识别超重、肥胖和中心性肥胖的腰围解剖点，并测试其切点与代谢综合征（MetS）、胰岛素抵抗（IR）和心脏代谢危险因素之间的关系。
300名男性[年龄：51（47 - 54）岁]接受了人体测量、身体成分、临床、社会人口统计学和血浆生化评估。
通过双能X线吸收法测量，脐线腰围（WCUL）是超重（全身脂肪≥20%；切点：88.8厘米）、肥胖（全身脂肪≥25%；切点：93.4厘米）和中心性肥胖（腹部脂肪≥34.6%；切点：95.6厘米）的最佳预测指标。WCUL≥88.8厘米或≥93.4厘米的受试者在MetS、IR和心脏代谢危险因素（即血糖和血脂谱、血压）方面的值显著更高。WCUL≥88.8厘米的发生率与MetS和心脏代谢危险因素的患病率呈正相关（p<0.01），并使中心性肥胖患病率增加19.3%，而WCUL≥93.4厘米的发生率与MetS、IR和心脏代谢危险因素的患病率相关。
WCUL测量似乎是巴西东南部城市中年男性超重、肥胖和中心性肥胖的最佳预测指标；并且在研究人群中，WCUL切点（88.8厘米）与MetS、IR和心脏代谢危险因素显著相关。
