Xu Gang, He Gang, Liu Bing, Xu Zhongming
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2014 Mar;28(5):314-7.
To improve the accuracy of diagnosis and treatment efficacy of hemangiopericytoma in nasal cavity and paranasal sinuses.
The clinical and pathological data of 5 cases with hemangiopericytoma in nasal cavity and paranasal sinuses verified by pathology were analyzed retrospectively.
Computed tomography scan revealed vascular in 5 cases. On CT scan, hemangiopericytoma generally appeared to be a uniform high density mass with obvious enhancement upon injection of contrast material. In pathological examination, there were plentiful capillaries which were like tree branch. The normal endocytes were in the inner wall of the vessel. The round, oval and spear-like pericytes scattered around the vessel. The split phase of the nucleus could be found in the tumor cell. All cases underwent surgical resection and were proved by pathological examination. The clinical data showed that the prognosis of sinonasal hemangiopericytoma was closely related to its histological grade. The recur rate in highly malignant hemangiopericytoma was obviously higher than that in middle and low malignant tumor. The rate of misdiagnosis was 80%.
Hemangiopericytoma is a potentially malignant tumor. Medical imaging can help to demonstrate the site, configuration, and characteristics of the tumors and contribute to the treatment. But there are not characteristic medical features. The final diagnosis must depend on the closely related to its pathological grade. The doctor should pay attention to the description of histological pathology. All the patients must be followed up carefully.
提高鼻腔鼻窦血管外皮细胞瘤的诊断准确性及治疗效果。
回顾性分析5例经病理证实的鼻腔鼻窦血管外皮细胞瘤患者的临床及病理资料。
计算机断层扫描显示5例均有血管影。CT扫描时,血管外皮细胞瘤一般表现为均匀的高密度肿块,增强扫描后强化明显。病理检查可见丰富的毛细血管,呈树枝状,血管内壁可见正常内皮细胞,圆形、椭圆形及梭形的周细胞散在分布于血管周围,肿瘤细胞可见核分裂相。所有病例均行手术切除并经病理检查证实。临床资料显示,鼻腔鼻窦血管外皮细胞瘤的预后与其组织学分级密切相关,高恶性血管外皮细胞瘤的复发率明显高于中低恶性肿瘤,误诊率为80%。
血管外皮细胞瘤是一种潜在恶性肿瘤。医学影像学有助于显示肿瘤的部位、形态及特征,对治疗有一定帮助,但无特征性影像学表现,最终诊断必须依靠与其病理分级密切相关的结果。医生应重视组织病理学描述,所有患者均需仔细随访。