El-Shabrawi Mortada H, Kamal Naglaa Mohamed, Kaerger Kerstin, Voigt Kerstin
Faculty of Medicine, Cairo University, Cairo, Egypt.
Mycoses. 2014 Dec;57 Suppl 3:138-43. doi: 10.1111/myc.12231. Epub 2014 Sep 3.
Basidiobolus ranarum (Entomophthoromycotina) very rarely affects the gastrointestinal (GI) tract. To date, reported paediatric GI basidiobolomycosis cases are 27 worldwide; 19 from Saudi Arabia and 8 from other parts of the world. Often these cases present a diagnostic dilemma, are prone to misdiagnosis and lack of disease confirmation by proper molecular methodologies. The fungal mass removed by surgery is usually sent for conciliar histopathology, isolation by fungal cultures and final molecular testing for basidiobolomycosis. The incidence of basidiobolomycoses, their predisposing factors and the molecular diagnosis of the fungus causing the disease in combination with a phylogenetic framework are reviewed.
蛙粪霉（虫霉目）极少累及胃肠道。迄今为止，全球报道的儿童胃肠道蛙粪霉病病例有27例；其中19例来自沙特阿拉伯，8例来自世界其他地区。这些病例常常面临诊断难题，容易误诊，且缺乏通过适当分子方法进行的疾病确诊。手术切除的真菌团块通常送去进行会诊组织病理学检查、真菌培养分离以及最终的蛙粪霉病分子检测。本文综述了蛙粪霉病的发病率、易感因素以及结合系统发育框架对引起该病的真菌进行分子诊断的情况。
