Meeralam Yaser, Basfar Abdulrahman M, Alzanbagi Adnan, Tashkandi Abdulaziz, Al Harthi Wallaa, Saba Firdos, Khairo Mutaz, Alzhrani Saleh, Shariff Mohammed
Gastroenterology, Digestive and Liver Center, King Abdullah Medical City, Makkah, SAU.
Pathology, King Abdullah Medical City, Makkah, SAU.
Cureus. 2024 Feb 26;16(2):e55008. doi: 10.7759/cureus.55008. eCollection 2024 Feb.
Gastrointestinal basidiobolomycosis (GIB) is a rare fungal infection caused by Basidiobolus ranarum, a saprophytic fungus that belongs to the class of Basidiobolomycetes. It mainly infects immunocompetent individuals and is mainly found in arid tropical and subtropical regions, including Southwestern America, Saudi Arabia, Africa, and Asia. Not surprisingly, a great number of human infections have been reported from these warm, humid climate regions that are felicitous for the growth of this fungus, especially from the southern region of Saudi Arabia and Arizona in the United States of America. GIB is easily misdiagnosed as malignancy, inflammatory bowel disease, diverticulitis, lymphoma, and chronic intestinal infections due to its rarity. In this case series, we summarize the clinical features, imaging, histopathological features, and treatment of patients diagnosed with GIB in our institution.
胃肠道蛙粪霉病(GIB)是一种由蛙粪霉引起的罕见真菌感染,蛙粪霉是一种腐生真菌,属于蛙粪霉纲。它主要感染免疫功能正常的个体,主要见于干旱的热带和亚热带地区,包括美国西南部、沙特阿拉伯、非洲和亚洲。不出所料,在这些有利于这种真菌生长的温暖潮湿气候地区,尤其是沙特阿拉伯南部地区和美国亚利桑那州,已经报告了大量人类感染病例。由于GIB较为罕见,它很容易被误诊为恶性肿瘤、炎症性肠病、憩室炎、淋巴瘤和慢性肠道感染。在本病例系列中,我们总结了在我们机构被诊断为GIB的患者的临床特征、影像学表现、组织病理学特征及治疗情况。