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新鲜样本尿沉渣细胞学与巴氏染色及吉姆萨染色涂片之间的相关性。

Correlation between the cytology of urine sediment in fresh sample and smears stained by Papanicolaou and Giemsa methods.

作者信息

Palaoro Luis Alberto, Angerosa Margarita

机构信息

Professor of Cytology, Clinical Hospital "José de San Martín", Buenos Aires University, Argentina ; Professor of Clinical Biochemistry, Instituto De Fisiopatologia Y Bioquimica Clinica, Argentina.

出版信息

J Cytol. 2014 Jan;31(1):25-31. doi: 10.4103/0970-9371.130666.

DOI:10.4103/0970-9371.130666
PMID:25190980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4150338/
Abstract

BACKGROUND

Urine excreted by the body has a variable composition in different physiological and pathological conditions. The cells that come from the renal pelvis, ureters, bladder, and urethra are carried by the urine, and therefore, they can be observed in fresh samples and in smears with Giemsa and Papanicolaou stain.

AIM

The aim of this study was to show that high correlation that exists between the cytological examination of fresh urine samples and smears stained with Papanicolaou and Giemsa methods.

MATERIALS AND METHODS

A total of 45 cases with no tumor of the urinary tract and 36 patients with lower urinary tract neoplasms were included in the study (20: Low-grade urothelial tumors; 16: High-grade urothelial tumors, squamous carcinomas, and adenocarcinomas). The sediments in the urine samples were observed in fresh specimen and in smears stained with Papanicolaou method.

RESULTS

The meticulous observation of fresh urinary sediments allowed identification of diverse cellular types associated with varied pathologies.

CONCLUSIONS

The cytological examination of urinary samples in fresh smears, and its later diagnostic confirmation with the Papanicolaou stain is important not only as a diagnostic procedure of tumoral or non-tumoral pathologies, but also as a method for the 'screening' of pre-cancerous lesions or carcinoma in situ, especially in high-risk populations.

摘要

背景

人体排出的尿液在不同生理和病理状态下成分各异。来自肾盂、输尿管、膀胱和尿道的细胞随尿液排出，因此可在新鲜样本以及经吉姆萨染色和巴氏染色的涂片中观察到。

目的

本研究的目的是表明新鲜尿液样本的细胞学检查与经巴氏法和吉姆萨法染色的涂片之间存在高度相关性。

材料与方法

本研究共纳入45例无尿路肿瘤的病例和36例下尿路肿瘤患者（20例：低级别尿路上皮肿瘤；16例：高级别尿路上皮肿瘤、鳞状细胞癌和腺癌）。在新鲜标本以及经巴氏法染色的涂片中观察尿液样本中的沉积物。

结果

对新鲜尿液沉积物的细致观察能够识别与各种病变相关的不同细胞类型。

结论

对新鲜涂片进行尿液样本的细胞学检查，随后用巴氏染色进行诊断确认，不仅作为肿瘤或非肿瘤病变的诊断程序很重要，而且作为一种对癌前病变或原位癌进行“筛查”的方法也很重要，尤其是在高危人群中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/14bf31cafa23/JCytol-31-25-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/d9136504811c/JCytol-31-25-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/b8bb7796f294/JCytol-31-25-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/a9d00d40ad3f/JCytol-31-25-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/0b45f9bb54fc/JCytol-31-25-g006.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/ca0a8a8238bf/JCytol-31-25-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/da9c3d6965d6/JCytol-31-25-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/923981b75ec4/JCytol-31-25-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/14bf31cafa23/JCytol-31-25-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/d9136504811c/JCytol-31-25-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/e3f629bcd547/JCytol-31-25-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/b8bb7796f294/JCytol-31-25-g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/0b45f9bb54fc/JCytol-31-25-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/ec07cb6e5fa1/JCytol-31-25-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/ca0a8a8238bf/JCytol-31-25-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/da9c3d6965d6/JCytol-31-25-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/923981b75ec4/JCytol-31-25-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c64/4150338/14bf31cafa23/JCytol-31-25-g011.jpg

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