WPI-Advanced Institute for Materials Research (WPI-AIMR), Tohoku University , Sendai 980-8577, Japan.
Org Lett. 2014 Sep 5;16(17):4670-3. doi: 10.1021/ol502285s. Epub 2014 Aug 25.
We have demonstrated for the first time that carboxylic acids are able to catalyze the direct hydroboration of various terminal and internal alkynes with pinacolborane without using any metal catalysts. This unprecedented catalytic hydroboration exhibits a broad functional groups compatibility, giving the corresponding alkenyl diboronates and monoboronates in good to high yields with exclusive regio- and stereoselectivities.
我们首次证明，羧酸无需使用任何金属催化剂就能催化各种末端和内部炔烃与频哪醇硼烷的直接硼氢化反应。这种前所未有的催化硼氢化反应具有广泛的官能团兼容性，能以良好到优异的收率和区域及立体选择性得到相应的烯基二硼酸盐和单硼酸盐。
