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针刺治疗中风后痉挛:随机对照试验的荟萃分析

Acupuncture for the treatment of spasticity after stroke: a meta-analysis of randomized controlled trials.

作者信息

Park Si-Woon, Yi Sook-Hee, Lee Jung Ah, Hwang Pil Woo, Yoo Hyun Cheol, Kang Kyoung Sook

机构信息

1 Department of Rehabilitation Medicine, Korea National Rehabilitation Center , Seoul, Korea.

出版信息

J Altern Complement Med. 2014 Sep;20(9):672-82. doi: 10.1089/acm.2014.0097.

Abstract

OBJECTIVES

Acupuncture has been suggested as a treatment for spasticity in patients with stroke. The available literature was reviewed in an effort to assess its efficacy in this situation.

METHODS

Randomized trials assessing the effects of acupuncture for the treatment of spasticity after stroke were identified by searching the Cochrane Library, PubMed, ProQuest, EBSCOhost, SCOPUS, CINAHL, EMBASE, Alternative Medicine Database, and Chinese and Korean medical literature databases. Two reviewers independently extracted data on study characteristics, patient characteristics, and spasticity outcomes.

RESULTS

Eight trials with 399 patients met all the inclusion criteria. Compared with controls without acupuncture, acupuncture had no effect on improving clinical outcomes (as measured by validated instruments such as the Modified Ashworth Scale) or physiologic outcomes (assessed by measures such as the H-reflex/M-response [H/M] ratio at the end of the treatment period). H/M ratios did decrease significantly immediately after the first acupuncture treatment. Methodologic quality of all evaluated trials was considered inadequate.

CONCLUSIONS

The effect of acupuncture for spasticity in patients with stroke remains uncertain, primarily because of the poor quality of the available studies. Larger and more methodologically sound trials are needed to definitively confirm or refute any effect of acupuncture as a treatment for spasticity after stroke.

摘要

目的

有人提出针刺疗法可用于治疗中风患者的痉挛。为评估其在这种情况下的疗效,对现有文献进行了综述。

方法

通过检索考克兰图书馆、PubMed、ProQuest、EBSCOhost、SCOPUS、CINAHL、EMBASE、替代医学数据库以及中国和韩国医学文献数据库,确定评估针刺疗法对中风后痉挛治疗效果的随机试验。两名评价者独立提取关于研究特征、患者特征和痉挛结局的数据。

结果

八项试验共399例患者符合所有纳入标准。与未接受针刺治疗的对照组相比,针刺疗法对改善临床结局(通过改良Ashworth量表等有效工具测量)或生理结局(通过治疗期末的H反射/M波幅[H/M]比值等测量)没有效果。第一次针刺治疗后,H/M比值立即显著下降。所有评估试验的方法学质量均被认为不足。

结论

针刺疗法对中风患者痉挛的疗效仍不确定,主要原因是现有研究质量较差。需要进行更大规模且方法学更合理的试验,以明确证实或反驳针刺疗法作为中风后痉挛治疗方法的任何效果。

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