来自菲律宾软珊瑚Lemnalia philippinensis的氧化桉叶烷型和新榄烷型倍半萜类化合物。

Oxygenated eremophilane- and neolemnane-derived sesquiterpenoids from the soft coral Lemnalia philippinensis.

作者信息

Xio Yun-Jie, Su Jui-Hsin, Tseng Yen-Ju, Chen Bo-Wei, Liu Wangta, Sheu Jyh-Horng

机构信息

Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.

Graduate Institute of Marine Biotechnology and Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan.

出版信息

Mar Drugs. 2014 Aug 15;12(8):4495-503. doi: 10.3390/md12084495.

DOI:10.3390/md12084495

PMID:25196835

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4145327/

Abstract

Five sesquiterpene-related metabolites (1-5), including two new eremophilane-type compounds, philippinlins C and D (1 and 2) and a 4,5-seconeolemnane philippinlin E (3), were isolated from the organic extract of a Taiwanese soft coral Lemnalia philippinensis. The structures of the new metabolites were determined on the basis of extensive spectroscopic analysis and by comparison of NMR data with those of related metabolites. Compound 3 was suggested to be derived from the neolemnane skeleton.

摘要

从台湾软珊瑚菲律宾列那海扇（Lemnalia philippinensis）的有机提取物中分离出了五种与倍半萜相关的代谢产物（1-5），其中包括两种新的艾里莫芬烷型化合物，菲律宾海扇灵C和D（1和2）以及一种4,5-断新海扇烷型菲律宾海扇灵E（3）。通过广泛的光谱分析并将核磁共振数据与相关代谢产物的数据进行比较，确定了这些新代谢产物的结构。化合物3被认为是由新海扇烷骨架衍生而来的。