de Mello Valéria, Prata Márcia Cristina de Azevedo, da Silva Márcio Roberto, Daemon Erik, da Silva Luciane Santos, Guimarães Flávia del Gaudio, de Mendonça Alessandra Esther, Folly Evelize, Vilela Fernanda Maria Pinto, do Amaral Lilian Henriques, Cabral Lucio Mendes, do Amaral Maria da Penha Henriques
Departamento Farmacêutico, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Campus Universitário, 36036-900, Juiz de Fora, Minas Gerais, Brazil.
Parasitol Res. 2014 Dec;113(12):4431-7. doi: 10.1007/s00436-014-4121-4. Epub 2014 Sep 10.
The cattle tick, Rhipicephalus (Boophilus) microplus, has caused serious harm to livestock raising in Brazil, considering the costs of controlling it, loss of revenue due to smaller production of milk and meat, and damage to leather, in addition to transmitting diseases. The use of medicinal plants is considered an alternative to the recurring resistance to chemicals. Due to the need for efficient alternatives with less environmental impact, this study aimed to develop contact formulations with essential oils from the Java citronella (Cymbopogon winterianus) and clove (Syzygium aromaticum) plants and to assess in vitro the effects in different stages of the tick cycle. In the present study, concentrations from 0.5-15.0% of the essential oils incorporated in the formulations were used. The ticks from different geographical areas were treated with those formulations, and their effects on the production levels of eggs, on the larvae hatching, and their efficiency on ticks were assessed. The obtained results were compared with other commercial acaricidal products. After the 20th day of treatment, the formulations with citronella essential oil had 2.09-55.51% efficiency, depending on the concentration of the oil incorporated. The efficiency of the treatment with formulations containing clove essential oil was higher, from 92.47-100%. The results showed the acaricidal effects of the formulations tested when compared to commercial chemical products. In vivo studies should be performed in order to assess the efficiency of those formulations in the fields, aiming to use these products as an alternative for controlling cattle ticks.
牛蜱，微小扇头蜱（Rhipicephalus (Boophilus) microplus），除了传播疾病外，还因控制成本、牛奶和肉类产量降低导致的收入损失以及皮革受损，给巴西的畜牧业造成了严重危害。考虑到化学药品反复出现耐药性问题，使用药用植物被视为一种替代方法。由于需要高效且对环境影响较小的替代方案，本研究旨在开发含有爪哇香茅（Cymbopogon winterianus）和丁香（Syzygium aromaticum）植物精油的接触型制剂，并在体外评估其对蜱虫生命周期不同阶段的影响。在本研究中，制剂中所含精油的浓度为0.5%至15.0%。用这些制剂处理来自不同地理区域的蜱虫，并评估其对蜱虫产卵量、幼虫孵化率的影响以及对蜱虫的防治效果。将所得结果与其他商业杀螨产品进行比较。处理第20天后，含香茅精油的制剂效率为2.09%至55.51%，具体取决于所含精油的浓度。含丁香精油制剂的处理效率更高，为92.47%至100%。结果表明，与商业化学产品相比，所测试的制剂具有杀螨效果。应进行体内研究，以评估这些制剂在田间的防治效果，旨在将这些产品用作控制牛蜱的替代方法。
