Lavender Jason M, Alosco Michael L, Spitznagel Mary Beth, Strain Gladys, Devlin Michael, Cohen Ronald, Paul Robert, Crosby Ross D, Mitchell James E, Wonderlich Stephen A, Gunstad John
Neuropsychiatric Research Institute, Fargo, ND, USA.
Kent State University, Kent, OH, USA.
J Psychiatr Res. 2014 Dec;59:148-54. doi: 10.1016/j.jpsychires.2014.08.004. Epub 2014 Aug 17.
Evidence suggests that both obesity and binge eating disorder (BED) may be associated with deficits in cognitive functioning. The purpose of this study was to examine whether a lifetime history of BED would be associated with changes in several domains of cognitive functioning (attention, executive function, language, and memory) following bariatric surgery. Participants were 68 bariatric surgery patients who completed a computerized battery of cognitive tests within 30 days prior to undergoing surgery and again at a 12-Month postoperative follow-up. Results revealed that on the whole, participants displayed improvements from baseline to follow-up in attention, executive function, and memory, even after controlling for diagnostic history of depression; no changes were observed for language. However, individuals with and without a history of BED did not differ in changes in body mass index or in the degree of improvement in cognitive functioning from baseline to follow-up. Such results suggest that a history of BED does not influence changes in cognitive functioning following bariatric surgery. Future research will be needed to further clarify the role of BED in predicting cognitive function over time.
有证据表明，肥胖和暴饮暴食症（BED）都可能与认知功能缺陷有关。本研究的目的是检验暴饮暴食症的终生病史是否与减肥手术后认知功能的几个领域（注意力、执行功能、语言和记忆）的变化有关。研究参与者为68名减肥手术患者，他们在手术前30天内完成了一组计算机化认知测试，并在术后12个月的随访中再次进行了测试。结果显示，总体而言，即使在控制了抑郁症诊断史之后，参与者从基线到随访在注意力、执行功能和记忆方面都有改善；语言方面未观察到变化。然而，有和没有暴饮暴食症病史的个体在体重指数变化或从基线到随访认知功能改善程度方面没有差异。这些结果表明，暴饮暴食症病史不会影响减肥手术后认知功能的变化。未来需要进一步的研究来进一步阐明暴饮暴食症在预测认知功能随时间变化方面的作用。
