Ho Yee-Hsien, Vora Hitesh D, Dahotre Narendra B
Laboratory for Laser Aided Additive and Subtractive Manufacturing, Department of Materials Science and Engineering, University of North Texas, Denton, TX, USA.
Laboratory for Laser Aided Additive and Subtractive Manufacturing, Department of Materials Science and Engineering, University of North Texas, Denton, TX, USA
J Biomater Appl. 2015 Feb;29(7):915-28. doi: 10.1177/0885328214551156. Epub 2014 Sep 8.
Magnesium alloys are the potential degradable materials for load-bearing implant application due to their comparable mechanical properties to human bone, excellent bioactivity, and in vivo non-toxicity. However, for a successful load-bearing implant, the surface of bio-implant must allow protein absorption and layer formation under physiological environment that can assist the cell/osteoblast growth. In this regard, surface wettability of bio-implant plays a key role to dictate the quantity of protein absorption. In light of this, the main objective of the present study was to produce favorable bio-wettability condition of AZ31B Mg alloy bio-implant surface via laser surface modification technique under various laser processing conditions. In the present efforts, the influence of laser surface modification on AZ31B Mg alloy surface on resultant bio-wettability was investigated via contact-angle measurements and the co-relationships among microstructure (grain size), surface roughness, surface energy, and surface chemical composition were established. In addition, the laser surface modification technique was simulated by computational (thermal) model to facilitate the prediction of temperature and its resultant cooling/solidification rates under various laser processing conditions for correlating with their corresponding composition and phase evolution. These predicted thermal properties were later used to correlate with the corresponding microstructure, chemical composition, and phase evolution via experimental analyses (X-ray diffractometer, scanning electron microscope, energy-dispersive spectroscopy).
镁合金因其与人体骨骼相当的力学性能、优异的生物活性以及体内无毒性,成为用于承重植入物的潜在可降解材料。然而,对于一个成功的承重植入物而言,生物植入物的表面必须在生理环境下允许蛋白质吸附并形成层,这有助于细胞/成骨细胞生长。在这方面,生物植入物的表面润湿性对于决定蛋白质吸附量起着关键作用。鉴于此,本研究的主要目的是通过激光表面改性技术,在各种激光加工条件下,使AZ31B镁合金生物植入物表面产生良好的生物润湿性条件。在目前的工作中,通过接触角测量研究了激光表面改性对AZ31B镁合金表面所得生物润湿性的影响,并建立了微观结构(晶粒尺寸)、表面粗糙度、表面能和表面化学成分之间的相互关系。此外,通过计算(热)模型对激光表面改性技术进行了模拟,以便预测各种激光加工条件下的温度及其产生的冷却/凝固速率,从而将其与相应的成分和相演变相关联。随后,通过实验分析(X射线衍射仪、扫描电子显微镜、能量色散光谱仪),将这些预测的热性能与相应的微观结构、化学成分和相演变相关联。