经激光加工和改性的医用 Ti-Mo 合金：兔的生物力学、组织学和组织计量学分析。
Biomedical Ti-Mo alloys with surface machined and modified by laser beam: biomechanical, histological, and histometric analysis in rabbits.
机构信息
Biomaterials Group, IQ, Universidade Estadual Paulista, UNESP, Araraquara, SP, Brazil.
出版信息
Clin Implant Dent Relat Res. 2013 Jun;15(3):427-37. doi: 10.1111/j.1708-8208.2011.00354.x. Epub 2011 May 9.
PURPOSE
In vivo bone response was assessed by removal torque, hystological and histometrical analysis on a recently developed biomedical Ti-15Mo alloy, after surface modification by laser beam irradiation, installed in the tibia of rabbits.
MATERIALS AND METHODS
A total of 32 wide cylindrical Ti-15Mo dental implants were obtained (10mm × 3.75mm). The implants were divided into two groups: 1) control samples (Machined surface - MS) and 2) implants with their surface modified by Laser beam-irradiation (Test samples - LS). Six implants of each surface were used for removal torque test and 10 of each surface for histological and histometrical analysis. The implants were placed in the tibial metaphyses of rabbits.
RESULTS
Average removal torque was 51.5Ncm to MS and >90Ncm to LS. Bone-to-implant-contact percentage was significantly higher for LS implants both in the cortical and marrow regions.
CONCLUSIONS
The present study demonstrated that laser treated Ti-15Mo alloys are promising materials for biomedical application.
目的
通过对最近开发的生物医学 Ti-15Mo 合金进行激光束辐照表面改性后的去除扭矩、组织学和组织计量学分析，评估其体内骨反应。
材料和方法
共获得 32 个宽圆柱形 Ti-15Mo 牙科植入物（10mm×3.75mm）。将植入物分为两组：1）对照样品（机械加工表面-MS）和 2）用激光束辐照表面改性的植入物（测试样品-LS）。每个表面的 6 个植入物用于去除扭矩测试，每个表面的 10 个植入物用于组织学和组织计量学分析。植入物放置在兔的胫骨干骺端。
结果
MS 的平均去除扭矩为 51.5Ncm，LS 的去除扭矩>90Ncm。LS 植入物的皮质和骨髓区域的骨-植入物接触百分比明显更高。
结论
本研究表明，激光处理的 Ti-15Mo 合金是生物医学应用的有前途的材料。
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