Powell David R, Patel Shiddhi, Franco-Paredes Carlos
Phoebe Putney Memorial Hospital (DRP, SP, CF-P), Infectious Diseases, Albany, Georgia; and Hospital Infantil de Mexico (CF-P), Federico Gomez, Mexico City, Mexico.
Am J Med Sci. 2015 Sep;350(3):243-5. doi: 10.1097/MAJ.0000000000000327.
Varicella-zoster virus (VZV) is herpes virus that after its reactivation from nerve ganglia to cause herpes zoster may lead to a variety of neurologic complications, including encephalitis, meningitis, retinal necrosis or myelitis. In addition, VZV can spread to arteries in the central nervous system and cause hemorrhagic or ischemic complications due to an inflammatory vasculopathy. In fact, there is a growing epidemiological and clinical recognition that there is an association between VZV reactivation and subsequent strokes. Herein, we present a case of an immune compromised individual with reactivation of VZV causing dermatomal herpes zoster followed by multifocal vasculopathy. We also review the literature to highlight key aspects of VZV-associated vasculopathy.
水痘带状疱疹病毒（VZV）是一种疱疹病毒，从神经节重新激活后引起带状疱疹，可能导致多种神经系统并发症，包括脑炎、脑膜炎、视网膜坏死或脊髓炎。此外，VZV可扩散至中枢神经系统的动脉，并由于炎症性血管病变导致出血性或缺血性并发症。事实上，越来越多的流行病学和临床研究认识到VZV重新激活与随后的中风之间存在关联。在此，我们报告一例免疫功能低下个体，VZV重新激活导致皮节带状疱疹，随后发生多灶性血管病变。我们还回顾了文献，以突出VZV相关血管病变的关键方面。
