Pote Sayali, Tiwari Pramil, D'cruz Sanjay
Department of Pharmacy Practice. National Institute of Pharmaceutical Education and Research, S. A. S. Nagar, Punjab ( India ).
Department of Medicine, Government Medical College and Hospital, Chandigarh ( India ).
Pharm Pract (Granada). 2007 Jan;5(1):17-20. doi: 10.4321/s1886-36552007000100003.
To prevent medication errors in prescribing, one needs to know their types and relative occurrence. Such errors are a great cause of concern as they have the potential to cause patient harm. The aim of this study was to determine the nature and types of medication prescribing errors in an Indian setting.
The medication errors were analyzed in a prospective observational study conducted in 3 medical wards of a public teaching hospital in India. The medication errors were analyzed by means of Micromedex Drug-Reax database.
Out of 312 patients, only 304 were included in the study. Of the 304 cases, 103 (34%) cases had at least one error. The total number of errors found was 157. The drug-drug interactions were the most frequently (68.2%) occurring type of error, which was followed by incorrect dosing interval (12%) and dosing errors (9.5%). The medication classes involved most were antimicrobial agents (29.4%), cardiovascular agents (15.4%), GI agents (8.6%) and CNS agents (8.2%). The moderate errors contributed maximum (61.8%) to the total errors when compared to the major (25.5%) and minor (12.7%) errors. The results showed that the number of errors increases with age and number of medicines prescribed.
The results point to the establishment of medication error reporting at each hospital and to share the data with other hospitals. The role of clinical pharmacist in this situation appears to be a strong intervention; and the clinical pharmacist, initially, could confine to identification of the medication errors.
为防止处方用药错误，人们需要了解其类型和相对发生率。此类错误令人极为担忧，因为它们有可能对患者造成伤害。本研究的目的是确定印度环境下处方用药错误的性质和类型。
在印度一家公立教学医院的3个内科病房进行的一项前瞻性观察研究中，对用药错误进行了分析。用药错误通过Micromedex Drug - Reax数据库进行分析。
在312名患者中，只有304名被纳入研究。在这304例病例中，103例（34%）至少有一处错误。发现的错误总数为157处。药物相互作用是最常出现的错误类型（68.2%），其次是给药间隔错误（12%）和剂量错误（9.5%）。涉及最多的药物类别是抗菌药物（29.4%）、心血管药物（15.4%）、胃肠道药物（8.6%）和中枢神经系统药物（8.2%）。与严重错误（25.5%）和轻微错误（12.7%）相比，中度错误在总错误中占比最大（61.8%）。结果表明，错误数量随着年龄和所开药物数量的增加而增加。
结果表明各医院应建立用药错误报告制度，并与其他医院共享数据。在这种情况下，临床药师的作用似乎是一种有力的干预措施；并且临床药师最初可以专注于识别用药错误。
