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本文引用的文献

1
An international survey on drug utilization during pregnancy.一项关于孕期药物使用情况的国际调查。
Int J Risk Saf Med. 1991;2(6):345-9. doi: 10.3233/JRS-1991-2606.
2
Prevalence of malaria during pregnancy and antimalarial intervention in an urban secondary health care facility in Southern Nigeria.尼日利亚南部一家城市二级医疗机构中孕期疟疾的患病率及抗疟干预措施
Med Princ Pract. 2007;16(3):240-3. doi: 10.1159/000100399.
3
A survey of knowledge, attitude and practice of malaria management among pregnant women from two health care facilities in Nigeria.尼日利亚两家医疗机构中孕妇疟疾管理知识、态度及实践的调查。
Acta Obstet Gynecol Scand. 2007;86(1):33-6. doi: 10.1080/00016340600984670.
4
Risk and benefit of drug use during pregnancy.孕期用药的风险与益处。
Int J Med Sci. 2005;2(3):100-6. doi: 10.7150/ijms.2.100. Epub 2005 Jul 1.
5
[Drug prescription for pregnant women: a pharmacoepidemiological study].[孕妇用药处方:一项药物流行病学研究]
Cad Saude Publica. 2004 Jul-Aug;20(4):1004-13. doi: 10.1590/s0102-311x2004000400015. Epub 2004 Jul 29.
6
Prescription of drugs to pregnant women in France: the HIMAGE study.法国孕妇用药情况:HIMAGE研究
Therapie. 2003 Nov-Dec;58(6):505-11. doi: 10.2515/therapie:2003082.
7
Prescription drugs and pregnancy.处方药与怀孕
Expert Opin Pharmacother. 2003 Jun;4(6):949-61. doi: 10.1517/14656566.4.6.949.
8
A study of drug use during pregnancy in a teaching hospital in western Nepal.尼泊尔西部一家教学医院的孕期用药情况研究。
Pharmacoepidemiol Drug Saf. 2003 Apr-May;12(3):221-5. doi: 10.1002/pds.770.
9
[Drug use by pregnant women in six Brazilian cities].[巴西六个城市孕妇的药物使用情况]
Rev Saude Publica. 2001 Oct;35(5):415-20. doi: 10.1590/s0034-89102001000500002.
10
Pattern of drug use amongst antenatal patients in Benin City, Nigeria.尼日利亚贝宁城产前患者的用药模式。
Med Sci Monit. 2000 Jan-Feb;6(1):84-7.

对前往产前诊所就诊的孕妇处方情况的评估。

Assessment of prescription profile of pregnant women visiting antenatal clinics.

作者信息

Eze Uchenna I, Eferakeya Adego E, Oparah Azuka C, Enato Ehijie F

机构信息

Department of Clinical Pharmacy/Biopharmacy, Faculty of Pharmacy, Olabisi Onabanjo University Shagamu Campus, Shagamu ( Nigeria ).

Department of Pharmacology &Toxicology, Faculty of Pharmacy, University of Benin , Benin City ( Nigeria ).

出版信息

Pharm Pract (Granada). 2007 Jul;5(3):135-9. doi: 10.4321/s1886-36552007000300007.

DOI:10.4321/s1886-36552007000300007
PMID:25214930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4154748/
Abstract

UNLABELLED

Managing medical complications in pregnancy is a challenge to clinicians.

OBJECTIVES

This study profiled some disease and prescription patterns for pregnant women attending antenatal clinics (ANCs) in Nigeria. A risk classification of the medicines was also determined.

METHODS

Medical case files of 1,200 pregnant women attending antenatal clinics of 3 health facilities in Benin City, Nigeria were investigated. Disease pattern was determined from their diagnoses. The prescription pattern was assessed using WHO indicators, and the United States Food and Drug Administration classification of medicines according to risk to the foetus.

RESULTS

A total of 1,897 prescriptions of the 1,200 pregnant women attendees during the period under review were evaluated. Results indicated that malaria 554 (38%) was the most prevalent disease, followed by upper respiratory tract infections (URTIs, 13%) and gastrointestinal disturbances (GIT, 12%). The average number of drugs prescribed per encounter was found to be 3.0, and 2,434 (43%) of medicines were prescribed by generic name. Minerals/ Vitamins 2,396 (42%) were the most frequently prescribed medicines, and antibiotics occurred in 502 (8.8%) of the total medicines. Of all medicines prescribed, 984 (17%) were included in the foetal risk category C and 286 (5%) in category D.

CONCLUSION

The study concluded that malaria fever occurred most frequently followed by URTIs and GIT disturbances among the pregnant women. Minerals, vitamins and to a less extent antimalarials topped the list of the prescribed medicines. The average number of medicines per encounter was much higher than WHO standards. The occurrence of contraindicated medicines was low.

摘要

未标注

孕期管理医疗并发症对临床医生来说是一项挑战。

目的

本研究剖析了尼日利亚产前诊所(ANC)就诊孕妇的一些疾病及处方模式。还确定了药物的风险分类。

方法

对尼日利亚贝宁城3家医疗机构产前诊所的1200名孕妇的医疗病例档案进行调查。根据诊断确定疾病模式。使用世界卫生组织指标评估处方模式,并根据药物对胎儿的风险采用美国食品药品监督管理局的药物分类。

结果

在审查期间,对1200名孕妇就诊者的1897份处方进行了评估。结果表明,疟疾554例(38%)是最常见的疾病,其次是上呼吸道感染(URTI,13%)和胃肠道紊乱(GIT,12%)。每次就诊平均开的药数为3.0种,2434种(43%)药物以通用名开具。矿物质/维生素2396种(42%)是最常开具的药物,抗生素占总药物数量的502种(8.8%)。在所有开具的药物中,984种(17%)属于胎儿风险C类,286种(5%)属于D类。

结论

该研究得出结论,孕妇中疟疾发热最为常见,其次是上呼吸道感染和胃肠道紊乱。矿物质、维生素以及较少程度的抗疟药在开具的药物中位居前列。每次就诊的平均药物数量远高于世界卫生组织标准。禁忌药物的出现率较低。