Department of Medicine/Division of Cardiology, Columbia University Medical Center, New York, NY.
Department of Medicine/Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI; Ann Arbor Veterans Affairs Health System, Ann Arbor, MI.
Prog Cardiovasc Dis. 2014 Sep-Oct;57(2):160-7. doi: 10.1016/j.pcad.2014.03.007. Epub 2014 Mar 12.
Dietary non-adherence to sodium restriction is an important contribution to heart failure (HF) symptom burden, particularly in older adults. While knowledge, skills, and attitudes toward sodium restriction are important, sodium intake is closely linked to the ability to taste salt. The 'hedonic shift' occurs when sodium restriction induces changes in an individual's salt taste that lower subsequent salt affinity. Older adults often have compromised salt taste and higher dietary salt affinity due to age-related changes. Older HF patients may have additional loss of salt taste and elevated salt appetite due to comorbid conditions, medication use, and micronutrient or electrolyte abnormalities, creating a significant barrier to dietary adherence. Induction of the hedonic shift has the potential to improve long-term dietary sodium restriction and significantly impact HF outcomes in older adults.
饮食上不遵守钠限制是心力衰竭(HF)症状负担的一个重要因素,尤其是在老年人中。虽然对钠限制的知识、技能和态度很重要,但钠的摄入量与味觉盐度密切相关。当钠限制引起个体盐味变化,降低随后的盐亲和力时,就会发生“愉悦度转移”。由于与年龄相关的变化,老年人的盐味往往受损,膳食盐亲和力更高。由于合并症、药物使用以及微量营养素或电解质异常,老年 HF 患者可能会进一步丧失盐味和升高的盐食欲,这给饮食依从性带来了重大障碍。愉悦度转移的诱导有可能改善长期的膳食钠限制,并对老年人的 HF 结局产生重大影响。