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死后利用体外受精剩余胚胎进行繁殖:一项探究使用者选择的研究。

Posthumous reproduction with surplus in vitro fertilization embryos: a study exploring users' choices.

机构信息

Service de médecine génique, Département de médecine, Centre hospitalier de l'Université de Montréal, Montréal, Québec, Canada; Programmes de bioéthique, Département de médecine sociale et préventive, École de santé publique de l'Université de Montréal, Université de Montréal, Montréal, Québec, Canada.

Programmes de bioéthique, Département de médecine sociale et préventive, École de santé publique de l'Université de Montréal, Université de Montréal, Montréal, Québec, Canada.

出版信息

Fertil Steril. 2014 Nov;102(5):1410-5. doi: 10.1016/j.fertnstert.2014.07.1202. Epub 2014 Sep 11.

Abstract

OBJECTIVE

To report results of analysis of in vitro fertilization (IVF) users' choices regarding the potential use of their surplus cryopreserved embryos for posthumous assisted reproduction (PAR).

DESIGN

Examination of signed consent forms.

SETTING

Public IVF clinic.

PATIENT(S): A total of 498 individuals who had signed consent forms for cryopreservation of surplus embryos.

INTERVENTION(S): Content analysis of consent form.

MAIN OUTCOME MEASURE(S): Agreement to PAR; importance of appropriate counseling within the consent process.

RESULT(S): Approximately 68% of individuals consented to the use of surplus embryos for embryologist training and improvement of assisted reproductive techniques, and 56% consented to the use of surplus embryos in a research project; 73.5% of men and 61.8% of women agreed to leave their cryopreserved embryos to their partners for reproductive use in the event of their death.

CONCLUSION(S): Our results demonstrate that a majority of both men and women agree to leave their frozen embryos to their partners for PAR in a "real life" context, i.e., in which they were required to provide consent for this prospective option. PAR involves complex issues, including the psychologic aspects of initiating a pregnancy while mourning the loss of a loved one or the effect on the prospective child. We argue that in light of the acceptability of PAR-as demonstrated by our results-further research is required regarding how to best counsel and inform IVF users about the choices they are making in this context, to ensure that their consent for PAR is in fact well informed.

摘要

目的

报告对体外受精(IVF)使用者选择使用其冷冻保存的多余胚胎进行死后辅助生殖(PAR)的潜在用途的分析结果。

设计

检查签署的同意书。

地点

公共 IVF 诊所。

患者

共 498 名签署了冷冻保存多余胚胎的同意书的个人。

干预

同意书内容分析。

主要观察指标

同意进行 PAR;同意过程中适当咨询的重要性。

结果

大约 68%的个人同意将多余胚胎用于胚胎学家培训和改进辅助生殖技术,56%同意将多余胚胎用于研究项目;73.5%的男性和 61.8%的女性同意在自己去世后将冷冻胚胎留给伴侣用于生殖用途。

结论

我们的结果表明,大多数男性和女性都同意在“现实生活”背景下将冷冻胚胎留给伴侣进行 PAR,即在需要为此类潜在选择提供同意的情况下。PAR 涉及复杂的问题,包括在哀悼亲人的同时开始怀孕的心理方面,或对潜在孩子的影响。我们认为,鉴于我们的研究结果表明 PAR 是可以接受的,因此需要进一步研究如何最好地为 IVF 用户提供咨询和信息,以确保他们对 PAR 的同意是知情的。

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