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获得性免疫缺陷综合征(艾滋病)中的心脏并发症:综述

Cardiac complications in acquired immunodeficiency syndrome (AIDS): a review.

作者信息

Acierno L J

机构信息

Department of Cardiopulmonary Sciences, College of Health, University of Central Florida, Orlando 32816.

出版信息

J Am Coll Cardiol. 1989 Apr;13(5):1144-54. doi: 10.1016/0735-1097(89)90277-5.

Abstract

Acquired immunodeficiency syndrome (AIDS) has become an increasingly important health problem worldwide. This review focuses on its cardiac complications. The key elements in the clinical syndrome are the opportunistic infections and the cancer that occur as a by-product of the immunodeficiency process. However, as early diagnosis, aggressive therapy and better supportive care become increasingly available, with consequently longer survival rates, cardiac lesions other than those due to opportunistic infections or malignancy should be seen. Cardiac complications are described in terms of the pathologic lesions, the clinical manifestations that ensue as a result of the pathologic lesions and the cardiac abnormalities that can occur from administration of the various therapeutic agents in the syndrome.

摘要

获得性免疫缺陷综合征(艾滋病)已成为全球范围内日益重要的健康问题。本综述聚焦于其心脏并发症。临床综合征的关键要素是机会性感染以及作为免疫缺陷过程副产品而出现的癌症。然而,随着早期诊断、积极治疗和更好的支持性护理越来越普及,生存率因此提高,除了由机会性感染或恶性肿瘤导致的心脏病变外,其他心脏病变也应会出现。本文将根据病理病变、由病理病变引发的临床表现以及该综合征中各种治疗药物使用可能导致的心脏异常来描述心脏并发症。

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