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儿科围手术期心脏骤停与死亡率:一项来自三级教学医院的研究。

Pediatric perioperative cardiac arrest and mortality: a study from a tertiary teaching hospital.

作者信息

Gonzalez Leopoldo P, Braz José R C, Módolo Marília P, de Carvalho Lídia R, Módolo Norma S P, Braz Leandro G

机构信息

1Department of Anesthesiology, Botucatu Medical School, UNESP-Univ Estadual Paulista, Botucatu, São Paulo, Brazil. 2Department of Biostatistics, Institute of Biosciences, UNESP-Univ Estadual Paulista, Botucatu, São Paulo, Brazil.

出版信息

Pediatr Crit Care Med. 2014 Nov;15(9):878-84. doi: 10.1097/PCC.0000000000000248.

Abstract

OBJECTIVES

A previous survey performed in our institution demonstrated perioperative pediatric cardiac arrest and mortality rates of 22.9 and 9.8 per 10,000 anesthetics, respectively, and an anesthesia-related cardiac arrest rate of 4.58 per 10,000 anesthetics. Changes in pediatric practices (i.e., safer anesthesia techniques and change in population) may have altered cardiac arrest rates. The aim of this investigation was to reexamine the perioperative and anesthesia-related cardiac arrest rates, causes, and outcomes in a Brazilian institution.

DESIGN

Observational study.

SETTING

Tertiary teaching hospital.

PATIENTS

Children less than 18 years old, who were administered an anesthetic between January 1, 2005, and December 31, 2010, were included in this study. The cardiac arrest cases were identified from an anesthesia database. The data included children's characteristics, surgical procedures, American Society of Anesthesiologists physical status classification, surgical areas, and surgery type. The outcomes were perioperative cardiac arrest and mortality and anesthesia-related (totally or partially) cardiac arrest and mortality.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

There were 10,649 anesthetics during the study period, with 22 perioperative cardiac arrests and 11 deaths (20.65 and 10.32 per 10,000 anesthetics, respectively). A high incidence of perioperative cardiac arrest occurred in American Society of Anesthesiologists IV-V neonates and infants who underwent emergency surgery. There were no perioperative cardiac arrests in children aged 13 through 17, no anesthesia-related cardiac arrest in American Society of Anesthesiologists I-III children, and no totally anesthesia-related cardiac arrest. The anesthesia-related cardiac arrest rate was 2.81 per 10,000 anesthetics, with no anesthesia-related mortality. Respiratory events accounted for all of the anesthesia-related cardiac arrests.

CONCLUSIONS

Despite the improvements achieved in the pediatric anesthesia safety in our institution, the perioperative cardiac arrest rates are still high and similar to the developing countries rates, with the child's disease or condition being the most important trigger for cardiac arrest. Airway management continues to be the greatest cause of anesthesia-related cardiac arrest.

摘要

目的

此前在我们机构进行的一项调查显示,围手术期小儿心脏骤停率和死亡率分别为每10000例麻醉22.9例和9.8例,麻醉相关心脏骤停率为每10000例麻醉4.58例。小儿麻醉实践的变化(即更安全的麻醉技术和人群变化)可能改变了心脏骤停率。本研究的目的是重新审视巴西一家机构的围手术期及麻醉相关心脏骤停率、原因和结局。

设计

观察性研究。

地点

三级教学医院。

患者

纳入2005年1月1日至2010年12月31日期间接受麻醉的18岁以下儿童。心脏骤停病例从麻醉数据库中识别。数据包括儿童特征、手术程序、美国麻醉医师协会身体状况分级、手术部位和手术类型。结局为围手术期心脏骤停和死亡率以及麻醉相关(全部或部分)心脏骤停和死亡率。

干预措施

无。

测量与主要结果

研究期间共进行了10649例麻醉,发生22例围手术期心脏骤停,11例死亡(分别为每10000例麻醉20.65例和10.32例)。美国麻醉医师协会IV - V级的新生儿和婴儿接受急诊手术时围手术期心脏骤停发生率较高。1

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