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益生元在新生儿腹股沟疝治疗中是否有一席之地?一项初步研究。

Is there a Place for Prebiotics in the Management of Neonatal Inguinal Hernia? A Preliminary Study.

作者信息

Dhaou Mahdi Ben, Zouari Mohamed, Ammar Saloua, Bouraoui Amira, Gassara Imene, Feki Ines, Zitouni Hayet, Jallouli Mohamed, Masmoudi Jawaher, Gargouri Abdellatif, Mhiri Riadh

机构信息

Department of Pediatric Surgery, Hedi Chaker Hospital, Sfax, Tunisia.

Department of Neonatology, Hedi Chaker Hospital, Sfax, Tunisia.

出版信息

J Neonatal Surg. 2017 Jan 1;6(1):7. doi: 10.21699/jns.v6i1.488. eCollection 2017 Jan-Mar.

Abstract

The objective of this study was to assess the place of prebiotics in the management of neonatal inguinal hernia. Boys with a diagnosis of unilateral non-complicated inguinal hernia, aged less than 40 days, were prospectively followed from January 2012 to December 2014. Clinical and psychiatric data and outcomes were collected before and after prebiotics (Primalac AC) administration. Ninety-eight patients were included. There were 75 inguinal hernias and 23 inguino-scrotal hernias. Before prebiotics administration 72.2% of infants had abdominal distention and 98% had colic. After prebiotics, abdominal distention and colic regressed in 85.2% and 73.2% of patients, respectively. Hernias disappeared clinically in 66.3% of cases. The factors associated with the disappearance of hernias were the type of the hernia (p<0.001), colic (p<0.001), and abdominal distention (p<0.001). Prebiotics would be a new adjunct in the management of neonatal inguinal hernia. They decrease colic and abdominal distention, which seems helpful to prevent strangulation and probably get spontaneous resolution of small hernias.

摘要

本研究的目的是评估益生元在新生儿腹股沟疝管理中的作用。对2012年1月至2014年12月期间年龄小于40天、诊断为单侧非复杂性腹股沟疝的男婴进行前瞻性随访。在给予益生元(Primalac AC)之前和之后收集临床和精神数据及结果。纳入了98例患者。其中有75例腹股沟疝和23例腹股沟阴囊疝。在给予益生元之前,72.2%的婴儿有腹胀,98%的婴儿有绞痛。给予益生元后,分别有85.2%和73.2%的患者腹胀和绞痛症状减轻。66.3%的病例中疝在临床上消失。与疝消失相关的因素有疝的类型(p<0.001)、绞痛(p<0.001)和腹胀(p<0.001)。益生元将成为新生儿腹股沟疝管理中的一种新辅助手段。它们可减轻绞痛和腹胀,这似乎有助于预防绞窄,并可能使小疝自行消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6c7/5224764/a3148fd7199c/jns-6-7.f1.jpg

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