Sue Paul K, Gurda Grzegorz T, Lee Richard, Watkins Tonya, Green Rachel, Memon Warda, Milstone Aaron M, Zelazny Adrian M, Fahle Gary A, Pham Thu Anh, Gibas Connie F, Sutton Deanna A, Wickes Brian L, Wiederhold Nathan P, Zhang Sean X
Division of Pediatric Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Division of Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
J Clin Microbiol. 2014 Dec;52(12):4407-11. doi: 10.1128/JCM.02012-14. Epub 2014 Sep 17.
Angioinvasive fungal infections (AFIs) are an important cause of morbidity and mortality among immunocompromised patients. However, clinicomicrobiological characteristics and treatment of many AFI agents remain poorly defined. We report the first human case of infection with Westerdykella dispersa, an emergent cause of AFI, which was successfully treated in a neutropenic pediatric patient.
血管侵袭性真菌感染（AFIs）是免疫功能低下患者发病和死亡的重要原因。然而，许多AFI病原体的临床微生物学特征和治疗方法仍不清楚。我们报告了首例人类感染分散韦斯特德氏菌的病例，这是一种新兴的AFI病原体，该病例在一名中性粒细胞减少的儿科患者中得到成功治疗。
