Scully Crispian
UCL - Eastman Dental Institute, London, UK.
BMJ Clin Evid. 2014 Sep 18;2014:1305.
Halitosis can be caused by oral disease or by respiratory tract conditions such as sinusitis, tonsillitis, and bronchiectasis, but an estimated 40% of affected individuals have no underlying organic disease.
We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments in people with physiological halitosis? We searched: Medline, Embase, The Cochrane Library, and other important databases up to July 2013 (Clinical evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
We found 11 studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
In this systematic review, we present information relating to the effectiveness and safety of the following interventions: artificial saliva; cleaning, brushing, or scraping the tongue; regular use of mouthwash; sugar-free chewing gums; and zinc toothpastes.
口臭可由口腔疾病或呼吸道疾病引起,如鼻窦炎、扁桃体炎和支气管扩张,但估计有40%的患者没有潜在的器质性疾病。
我们进行了一项系统评价,旨在回答以下临床问题:生理性口臭患者接受治疗的效果如何?我们检索了:截至2013年7月的医学期刊数据库(Medline)、荷兰医学文摘数据库(Embase)、考克兰图书馆及其他重要数据库(临床证据综述会定期更新;请查阅我们的网站获取本综述的最新版本)。我们纳入了来自美国食品药品监督管理局(FDA)和英国药品及医疗保健产品监管局(MHRA)等相关组织的危害警示。
我们发现11项研究符合我们的纳入标准。我们对干预措施的证据质量进行了GRADE评估。
在本系统评价中,我们提供了有关以下干预措施有效性和安全性的信息:人工唾液;清洁、刷牙或刮舌;定期使用漱口水;无糖口香糖;以及含锌牙膏。