A Gohar Ahmed, T Maatooq Galal, R Gadara Sahar, S Aboelmaaty Walaa, M El-Shazly Atef
Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt .
Parasitology Department, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.
Iran J Pharm Res. 2014 Spring;13(2):505-14.
Methanol extracts of Callistemon viminalis (Sol. Ex Gaertner) G.Don Ex Loudon fruits, bark and leaves were tested for molluscicidal activity. Snails were collected and kept in dechlorinated water under standard condition. Ten adults Biomphalaria Alexandrina, of the same size, were introduced in plastic acquaria for each experiment. The fruits, barks and leaves were extracted with methanol and the methanol extracts were kept for testing as molluscicides. Different extracts proved to have molluscicidal activity against the vector of schistosomiasis, B. alexandrina snails. LC50 values for C. viminalis fruits, bark and leaves were 6.2, 32 and 40 ppm respectively. The C. viminalis fruits extract showed the highest effect against the tested snails. Histopathological studies proved that the site of action of all tested extracts was localized in the digestive system and hermaphrodite gland.
对细枝红千层（Sol. Ex Gaertner）G.Don Ex Loudon的果实、树皮和树叶的甲醇提取物进行了杀螺活性测试。收集蜗牛并在标准条件下饲养于去氯水中。每次实验时，将10只大小相同的成年埃及双脐螺放入塑料水族箱中。用甲醇对果实、树皮和树叶进行提取，并将甲醇提取物留作杀螺剂测试。不同提取物对血吸虫病传播媒介埃及双脐螺显示出杀螺活性。细枝红千层果实、树皮和树叶的半数致死浓度（LC50）值分别为6.2、32和40 ppm。细枝红千层果实提取物对受试蜗牛的效果最佳。组织病理学研究证明，所有受试提取物的作用部位均位于消化系统和雌雄同体腺。
