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中国儿童微量营养素缺乏现象:文献系统综述

The phenomenon of micronutrient deficiency among children in China: a systematic review of the literature.

作者信息

Wong Angel Y S, Chan Esther W, Chui Celine S L, Sutcliffe Alastair G, Wong Ian C K

机构信息

1Centre for Safe Medication Practice and Research,Department of Pharmacology and Pharmacy,Li Ka Shing Faculty of Medicine,The University of Hong Kong,2/F Laboratory Block,21 Sassoon Road,Hong Kong Special Administrative Region,People's Republic of China.

2General and Adolescent Paediatric Unit,UCL Institute of Child Health,University College London,London,UK.

出版信息

Public Health Nutr. 2014 Nov;17(11):2605-18. doi: 10.1017/S1368980013002978.

Abstract

OBJECTIVE

The present study aimed to review the literature on micronutrient deficiency and other factors influencing a deficiency status among children living in China.

DESIGN

A systematic review was performed to analyse the literature.

SETTING

Studies were identified through a search of PubMed and secondary references.

SUBJECTS

Children living in China aged less than 18 years.

RESULTS

Sixty-one articles were included. The prevalence of vitamin A deficiency decreased to approximately 10 % in 1995-2009. It increased with age but no significant difference was found between genders. The prevalence of thiamin and vitamin B12 deficiency was 10·5 % in Yunnan and 4·5 % in Chongqing provinces, respectively. Higher vitamin D deficiency rates were seen in spring and winter. The incidence of bleeding due to vitamin K deficiency was 3·3 % in 1998-2001 and more prevalent in rural areas. Both iodine deficiency and excess iodine intake were observed. Goitre rates were reported in Tibet, Jiangxi, Gansu and Hong Kong (3·5-46 %). Anaemia rates ranged from 20 % to 40 % in 2007-2011. High Se deficiency rates were found in Tibet, Shaanxi and Jiangsu. High Zn deficiency rates were also found (50-70 %) in 1995-2006. Few studies reported Ca deficiency rates (19·6-34·3 %). The degrees of deficiency for vitamin A, vitamin B12, Fe and Zn were more substantial in rural areas compared with urban areas.

CONCLUSIONS

The prevalence of micronutrient deficiency rates varied. Socio-economic status, environmental factors and the Chinese diet may influence micronutrient deficiency. Public health policies should consider implementing programmes of supplementation, food fortification and nutrition education to address these deficiencies among Chinese children.

摘要

目的

本研究旨在综述关于中国儿童微量营养素缺乏及其他影响缺乏状况的因素的文献。

设计

进行系统综述以分析文献。

背景

通过检索PubMed及二次参考文献来确定研究。

研究对象

居住在中国的18岁以下儿童。

结果

纳入61篇文章。1995 - 2009年维生素A缺乏患病率降至约10%。其患病率随年龄增加,但性别间无显著差异。硫胺素和维生素B12缺乏患病率在云南省分别为10.5%,在重庆为4.5%。冬春季节维生素D缺乏率更高。1998 - 2001年维生素K缺乏导致出血的发生率为3.3%,在农村地区更普遍。碘缺乏和碘摄入过量均有观察到。西藏、江西、甘肃和香港报告有甲状腺肿患病率(3.5% - 46%)。2007 - 2011年贫血率在20%至40%之间。西藏、陕西和江苏发现高硒缺乏率。1995 - 2006年也发现高锌缺乏率(50% - 70%)。很少有研究报告钙缺乏率(19.6% - 34.3%)。与城市地区相比,农村地区维生素A、维生素B12、铁和锌的缺乏程度更严重。

结论

微量营养素缺乏率各不相同。社会经济状况、环境因素和中国饮食可能影响微量营养素缺乏。公共卫生政策应考虑实施补充、食品强化和营养教育计划以解决中国儿童的这些缺乏问题。

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