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眼球突出和面神经麻痹作为急性髓系白血病的一种不寻常临床表现。

Proptosis and facial palsy as an unusual clinical presentation of acute myeloid leukemia.

作者信息

Takhenchangbam Dhaneshor Sharma, Laishram Rajesh Singh, Thoudem Tomcha Singh, Sunita Akoijam, Imchen Lanu Tiameren

机构信息

Dept. of Radiotherapy, Regional Institute of Medical Sciences, Imphal, Manipur, India.

Dept. of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur, India.

出版信息

Iran J Cancer Prev. 2013 Winter;6(1):52-4.

Abstract

Simultaneous proptosis and facial palsy as the clinical presentation of childhoodAcute Myeloid Leukaemia (AML) is very rare. To date, no case have beenreported anywhere to the best of our knowledge. Extra medullary leukemic deposits or Granulocytic Sarcoma (GS) is a rare manifestation in about 3% of childhood AML, 9.3% of GS manifested as orbit deposits causing proptosis in one or both eyes. CNS infiltration or acute otomastoiditis subsequent to leukemic infiltration of the temporal bone may be implicated with facial paralysis. We are here with reporting the case in a 3-year-old boy who presented with proptosis and facial palsy in a case of AML. The purpose of reporting this case is to emphasize the need of examining the peripheral blood and bone marrow in children presenting as proptosis and facial palsy for early diagnosis of childhood AML.

摘要

同时出现眼球突出和面神经麻痹作为儿童急性髓系白血病(AML)的临床表现非常罕见。据我们所知,迄今为止,尚无任何地方报道过此类病例。髓外白血病沉积或粒细胞肉瘤(GS)是儿童AML中约3%的罕见表现,9.3%的GS表现为眼眶沉积,导致一只或两只眼睛突出。中枢神经系统浸润或颞骨白血病浸润后的急性耳乳突炎可能与面神经麻痹有关。我们在此报告一名3岁男孩的病例,该男孩在AML病例中出现眼球突出和面神经麻痹。报告此病例的目的是强调对于出现眼球突出和面神经麻痹的儿童,需要检查外周血和骨髓以早期诊断儿童AML。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b93d/4142910/4c8852fd59a4/IJCP-06-052f1.jpg

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