社区获得性和医院获得性化脓性皮肤及软组织感染中耐甲氧西林金黄色葡萄球菌的患病率

Prevalence of methicillin resistant Staphylococcus aureus in pyogenic community and hospital acquired skin and soft tissues infections.

作者信息

Ahmad Muhammad Khurram, Asrar Asma

出版信息

J Pak Med Assoc. 2014 Aug;64(8):892-5.

Abstract

OBJECTIVE

To determine the percentage and frequency of Methicillin Resistant Staphylococcus aureus in community and hospital-acquired pyogenic skin and soft tissue infections.

METHODS

The descriptive cross-sectional study was conducted at the Dermatology Department of Combined Military Hospital, Abbottabad, from June 2009 to March 2010, and comprised 144 community-acquired and 54 hospital-acquired skin and soft tissue infections. Pus swabs from the infected lesions one from each individual were sent to laboratory for culture and sensitivity tests. Methicillin resistance was detected by 1 microg oxacillin disk. Organisms were labelled methicillin-resistant once the inhibition zone for oxocillin was less than 10 mm. Data analysis was done by using SPSS 20.

RESULTS

Of the 198 patients in the study, 98 (49.5%) were males and 100 (50.5%) were females, with an overall mean age of 33.7 +/- 14.81 44 years. There were 144 (72.72%) community-acquired infections and 54 (27.27%) had hospital-acquired infections. Community-acquired Methicillin Resistant Staphylococcus aureus numbered 40 (27.8%) and hospital-acquired ones numbered 26 (48.1%).

CONCLUSION

Prevalence of Methicillin Resistant Staphylococcus aureus in community and hospital-acquired pyogenic skin and soft tissue infections was high.

摘要

目的

确定社区获得性和医院获得性化脓性皮肤及软组织感染中耐甲氧西林金黄色葡萄球菌的百分比和发生率。

方法

2009年6月至2010年3月在阿伯塔巴德联合军事医院皮肤科进行了描述性横断面研究，纳入144例社区获得性和54例医院获得性皮肤及软组织感染患者。从每个患者的感染病灶采集脓液拭子，送实验室进行培养和药敏试验。采用1μg苯唑西林纸片检测耐甲氧西林情况。一旦苯唑西林抑菌圈小于10mm，菌株即被标记为耐甲氧西林。使用SPSS 20进行数据分析。

结果

本研究的198例患者中，男性98例（49.5%），女性100例（50.5%），总体平均年龄为33.7±14.81岁。社区获得性感染144例（72.72%），医院获得性感染54例（27.27%）。社区获得性耐甲氧西林金黄色葡萄球菌40例（27.8%），医院获得性耐甲氧西林金黄色葡萄球菌26例（48.1%）。