Department of Dermatology and Pediatric Dermatology, National Centre for Rare Skin Disorders, Hôpital Pellegrin and University of Bordeaux and Inserm U1035, Bordeaux, France.
Br J Dermatol. 2015 Mar;172(3):716-21. doi: 10.1111/bjd.13423. Epub 2014 Dec 11.
Hypochromic vitiligo is a rare entity that has been reported only twice under the term 'vitiligo minor', with an absence of clear delineation.
To delineate hypochromic vitiligo through a case series of patients with typical bilateral hypopigmented lesions affecting the face and trunk.
This is a retrospective multicentric evaluation study conducted in eight departments of dermatology in France, Belgium, Senegal and Saudi Arabia.
Twenty-four cases of hypochromic vitiligo were identified. Fourteen were men and 10 women. The mean age at diagnosis was 35·4 years (range 8-66). Strikingly, all patients were dark skinned, with skin types V and VI. The pattern of distribution was highly similar in most of the patients (18 of 24), with involvement of the face and neck area predominating on seborrhoeic areas associated with multiple isolated hypopigmented macules involving predominantly the scalp. The retrospective nature of this study is its main limitation.
Hypochromic vitiligo is not yet part of a conventional classification. The disease seems to be limited to individuals with dark skin types. Hypopigmented seborrhoeic face and neck involvement associated with hypopigmented macules of the trunk and scalp is the hallmark of the disease.
色素减退性白癜风是一种罕见的疾病，仅在“白癜风小型”这一术语下被报道过两次，且没有明确的界定。
通过一系列典型的双侧色素减退性病变影响面部和躯干的患者病例系列，对色素减退性白癜风进行界定。
这是一项在法国、比利时、塞内加尔和沙特阿拉伯的 8 个皮肤科部门进行的回顾性多中心评估研究。
共发现 24 例色素减退性白癜风病例。14 例为男性，10 例为女性。诊断时的平均年龄为 35.4 岁（范围 8-66 岁）。引人注目的是，所有患者的皮肤均为深色，皮肤类型为 V 型和 VI 型。大多数患者（24 例中的 18 例）的分布模式非常相似，面部和颈部区域受累，皮脂溢出部位为主，伴有多个孤立的色素减退性斑，主要累及头皮。本研究的主要局限性在于其回顾性。
色素减退性白癜风尚未被纳入常规分类。这种疾病似乎仅限于深色皮肤类型的个体。色素减退性皮脂溢出性面部和颈部受累，伴发躯干和头皮的色素减退性斑，是这种疾病的标志。
