Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, 134 Sinchon-dong, Seodaemun-gu, Seoul 120-752, Korea.
Br J Dermatol. 2011 May;164(5):1004-9. doi: 10.1111/j.1365-2133.2010.10202.x. Epub 2011 Apr 5.
The origin of the distribution of segmental vitiligo (SV) has not yet been clearly elucidated. Segmental configurations of cutaneous disorders have been explained using two main interpretations, i.e. following either dermatomal or blaschkolinear distributions. However, facial SV does not always correspond to either of these distributions.
We classified facial SV into several distinctive subtypes according to specific distributions based on long-term observations.
In total, 257 patients with facial SV were included, all of whom were closely observed for more than 1 year. The distribution patterns of facial SV were classified according to morphological similarities based on clinical observations.
The lesions of facial SV were categorized into six subtypes: types I-a and I-b, and types II-V. Type I-a and type IV broadly involved the mid-level face from the forehead to the lower cheek, but type IV lesions selectively appeared on the right side of the face and did not cross the midline. Type I-b lesions chiefly involved the forehead and scalp hair. Types II and III involved the lower face and, frequently, the neck area, and type V lesions were distributed mostly around the right orbital area. The most frequent type of lesion in this study was type I-a (28·8%), followed by types II (16·0%), III (14·4%), IV (10·9%), I-b (10·5%) and V (8·6%).
Newly established patterns of facial SV may be valuable for certain aspects of prognosis, such as the likely degree and path of lesion spreading.
节段性白癜风(SV)的发病部位尚未明确。皮肤疾病的节段性分布可以用两种主要的解释来解释,即皮节或 Blaschko 线分布。然而,面部 SV 并不总是符合这两种分布之一。
我们根据长期观察将面部 SV 分为几种不同的亚型。
共纳入 257 例面部 SV 患者,所有患者均密切观察 1 年以上。根据临床观察的形态学相似性,对面部 SV 的分布模式进行分类。
面部 SV 的皮损分为六型:I-a 和 I-b 型,以及 II-V 型。I-a 型和 IV 型广泛累及面部中线从额头到下颌的中水平,但 IV 型皮损选择性地出现在面部右侧,不跨越中线。I-b 型皮损主要累及额头和头皮毛发。II 型和 III 型累及下面部,常累及颈部区域,V 型皮损主要分布在右侧眶周区域。本研究中最常见的皮损类型是 I-a 型(28.8%),其次是 II 型(16.0%)、III 型(14.4%)、IV 型(10.9%)、I-b 型(10.5%)和 V 型(8.6%)。
新建立的面部 SV 模式可能对某些预后方面有价值,如病变扩散的可能程度和途径。