Department of General Surgery, the First Hospital of China Medical University, 155 North Nanjing Street, Heping District, Shenyang 110001, China.
World J Surg Oncol. 2014 Sep 25;12:299. doi: 10.1186/1477-7819-12-299.
Pancreatic metastases (PMs) are rare and lack of guidelines for diagnosis and treatments .The aim of this study is to explore the diagnosis, treatment, and prognosis of pancreatic metastases.
Twenty-two patients with pancreatic metastases who had been hospitalized at the First Affiliated Hospital of China Medical University from October 1980 to October 2012 were included in the present retrospective study. Seven patients had gastric cancer, five had colon cancer, two each had lung and liver cancer, and one each had bladder cancer, gallbladder cancer, breast cancer, nasopharyngeal cancer, renal cell carcinoma, and carcinoid.
No specific syndrome or imageological change was found for the pancreatic metastases. The most common symptoms were abdominal pain and jaundice. Hypo-echoic lesions with well-defined margins were found on ultrasonic examinations, and low-density lesions with heterogeneous enhancement were identified in CT images. Nineteen of the 22 received treatment. Three of the 8 patients (34.1%) that had undergone operation experienced complications, but all patients recovered after conventional treatment. Follow-up studies were performed for 17 patients (77.3%), and the median survival time from the diagnosis of pancreatic metastases was 13.2 months (range, 2 to 68 months). Of the five patients who underwent radical resection, one was lost to follow-up, one died at fifteen months postoperation, and the other three are still alive and free from disease (disease-free survival ranging from five to thirty-three months from the diagnosis of the pancreatic metastases).
Pancreatic metastases are rare lesions with no specific symptoms. Radical resection should be performed if possible; however, aggressive treatment should be performed for unresectable pancreatic metastases.
胰腺转移瘤（PM）较为罕见，其诊断和治疗缺乏指南。本研究旨在探讨胰腺转移瘤的诊断、治疗和预后。
回顾性分析 1980 年 10 月至 2012 年 10 月中国医科大学附属第一医院收治的 22 例胰腺转移瘤患者的临床资料。7 例患者原发病为胃癌，5 例为结肠癌，2 例分别为肺癌和肝癌，1 例分别为膀胱癌、胆囊癌、乳腺癌、鼻咽癌、肾细胞癌和类癌。
胰腺转移瘤无特异性症状或影像学改变，最常见的症状为腹痛和黄疸。超声检查可见边界清楚的低回声病灶，CT 图像可见混杂密度的低密度病灶，不均匀强化。22 例患者中 19 例接受治疗，8 例行手术的患者中 3 例（34.1%）出现并发症，但均经常规治疗后痊愈。对 17 例患者进行随访，中位生存时间为 13.2 个月（268 个月）。5 例行根治性切除术的患者中，1 例失访，1 例术后 15 个月死亡，3 例无瘤生存，生存时间 533 个月。
胰腺转移瘤较为罕见，无特异性症状。如果可能，应行根治性切除术；对于无法切除的胰腺转移瘤，应采取积极的治疗措施。
