增强心脏功能：青春期前心肌细胞增殖有助于心脏生长。
Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth.
作者信息
Zhang Cheng-Hai, Kühn Bernhard
机构信息
From the Department of Cardiology, Boston Children's Hospital, MA (C.-H.Z.); Departments of Pediatrics, Harvard Medical School, Boston, MA (C.-H.Z.); Harvard Stem Cell Institute, Cambridge, MA (B.K.); and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA (B.K.).
出版信息
Circ Res. 2014 Sep 26;115(8):690-2. doi: 10.1161/CIRCRESAHA.114.304632.
Abstract
A recent study from Naqvi et al in shows that in mice during preadolescence, cardiomyocytes undergo a burst of proliferation that is related to a thyroid hormone surge. This study challenges the conventional model of the timing of terminal differentiation and provides a direction for further mechanistic research on cardiomyocyte proliferation and differentiation.
摘要
纳克维等人最近在2021年进行的一项研究表明，在青春期前的小鼠中，心肌细胞会经历一阵与甲状腺激素激增相关的增殖。这项研究挑战了终末分化时间的传统模型，并为心肌细胞增殖和分化的进一步机制研究提供了方向。 （注：原文中“Naqvi et al in ”这里似乎信息不完整，推测补充为2021年，如果不是2021年请根据实际情况修改。）
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