Treibel T A, White S K, Moon J C
Department of Cardiology, The Heart Hospital, University College London Hospitals NHS Trust, London, UK.
Department of Cardiology, The Heart Hospital, University College London Hospitals NHS Trust, London, UK ; The Heart Hospital Imaging Centre, University College London Hospitals NHS Trust, 16-18 Westmoreland Street, London, W1G 8PH UK.
Curr Cardiovasc Imaging Rep. 2014;7(3):9254. doi: 10.1007/s12410-013-9254-9.
Cardiovascular magnetic resonance imaging (CMR) has become the gold standard not only for cardiac volume and function quantification, but for a key unique strength: non-invasive myocardial tissue characterization. Several different techniques, separately or in combination, can detect and quantify early and established myocardial pathological processes permitting better diagnosis, prognostication and tracking of therapy. The authors will focus on the histological and pathophysiological evidence of these imaging parameters in the characterization of edema, infarction, scar and fibrosis. In addition to laying out the strengths and weaknesses of each modality, the reader will be introduced to rapid developments in T1 and T2 mapping as well as the use of contrast-derived extracellular volume for quantification of diffuse fibrosis.
心血管磁共振成像（CMR）不仅已成为心脏容积和功能定量的金标准，还具有一项关键的独特优势：无创心肌组织特征分析。几种不同的技术单独或联合使用，能够检测并量化早期和已形成的心肌病理过程，从而实现更好的诊断、预后评估以及治疗跟踪。作者将重点关注这些成像参数在水肿、梗死、瘢痕和纤维化特征分析中的组织学和病理生理学证据。除了阐述每种方法的优缺点外，还将向读者介绍T1和T2映射的快速发展，以及利用对比剂衍生的细胞外容积来定量弥漫性纤维化。
