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脊柱弥漫性特发性骨肥厚(DISH):背痛的一个原因?一项对照研究。

Diffuse idiopathic skeletal hyperostosis (DISH) of the spine: a cause of back pain? A controlled study.

作者信息

Schlapbach P, Beyeler C, Gerber N J, van der Linden S, Bürgi U, Fuchs W A, Ehrengruber H

机构信息

Department of Rheumatology, University of Berne, Inselspital, Switzerland.

出版信息

Br J Rheumatol. 1989 Aug;28(4):299-303. doi: 10.1093/rheumatology/28.4.299.

Abstract

This is the first controlled study of the frequency of back pain in a European caucasian population with diffuse idiopathic skeletal hyperostosis (DISH). Elderly patients admitted to hospital for reasons other than back pain were assessed for the presence of spinal DISH using the routine lateral chest radiograph films. A total of 106 probands (82 males, 24 females) with a mean age of 70 years fulfilled the criteria for DISH as defined previously. One hundred and seventy-eight patients (117 males, 61 females) not meeting these criteria were used as controls. The prevalence of back pain was assessed by a blinded interviewer using a structured questionnaire. Our primary hypothesis was that spinal DISH positive probands had not had back pain more often than controls. This controlled study showed no statistically significant difference in pain frequency between spinal DISH positive probands and controls at any spinal level. We conclude that back pain does not occur more often in radiographically defined DISH positive probands than in controls. The radiological finding of spinal DISH, as far as it does not lead to stenosis of the spinal canal or dysphagia, thus seems to be a finding without clinical relevance.

摘要

这是对欧洲白种人弥漫性特发性骨肥厚(DISH)患者背痛发生率的首次对照研究。因非背痛原因入院的老年患者,通过常规胸部侧位X线片评估脊柱DISH的存在情况。共有106名平均年龄为70岁的先证者(82名男性,24名女性)符合先前定义的DISH标准。178名不符合这些标准的患者(117名男性,61名女性)作为对照。由一名不知情的访谈者使用结构化问卷评估背痛的患病率。我们的主要假设是,脊柱DISH阳性的先证者背痛的发生频率并不高于对照组。这项对照研究表明,在任何脊柱节段,脊柱DISH阳性先证者与对照组之间的疼痛频率在统计学上均无显著差异。我们得出结论,影像学定义的DISH阳性先证者背痛的发生率并不高于对照组。因此,脊柱DISH的影像学表现,只要不导致椎管狭窄或吞咽困难,似乎就是一种无临床意义的表现。

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