Department of Preventive Medicine, Jeju National University School of Medicine, Jeju, Korea.
Epidemiol Health. 2014 Sep 26;36:e2014020. doi: 10.4178/epih/e2014020. eCollection 2014.
Breast cancer, the second leading type of cancer in Korean women, has shown increasing incidence over the past 10 years. However, the curves of incidence by age group cast doubt on the birth cohort effect hypothesis. To explain the curves, here I suggest two alternative hypotheses of breast density and viral infection based on pre-existing evidences. Evaluating these hypotheses would require important clues to find unknown risk factors of breast cancer and to plan more effective strategies for breast cancer control in Korean women.
乳腺癌是韩国女性第二大常见癌症类型,在过去 10 年中发病率呈上升趋势。然而,按年龄组划分的发病率曲线对出生队列效应假说提出了质疑。为了解释这些曲线,我根据现有证据提出了两个基于乳腺密度和病毒感染的替代假说。评估这些假说需要重要的线索来寻找乳腺癌未知的危险因素,并为韩国女性制定更有效的乳腺癌控制策略。