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保护性回肠造口关闭延迟后术后并发症增加:一项机构研究。

Increased postoperative complications after protective ileostomy closure delay: An institutional study.

机构信息

Ines Rubio-Perez, Miguel Leon, Daniel Pastor, Joaquin Diaz Dominguez, Ramon Cantero, General and Digestive Surgery Department, La Paz University Hospital, 28046 Madrid, Spain.

出版信息

World J Gastrointest Surg. 2014 Sep 27;6(9):169-74. doi: 10.4240/wjgs.v6.i9.169.

Abstract

AIM

To study the morbidity and complications associated to ileostomy reversal in colorectal surgery patients, and if these are related to the time of closure.

METHODS

A retrospective analysis of 93 patients, who had undergone elective ileostomy closure between 2009 and 2013 was performed. Demographic, clinical and surgical variables were reviewed for analysis. All complications were recorded, and classified according to the Clavien-Dindo Classification. Statistical univariate and multivariate analysis was performed, setting a P value of 0.05 for significance.

RESULTS

The patients had a mean age of 60.3 years, 58% male. The main procedure for ileostomy creation was rectal cancer (56%), and 37% had received preoperative chemo-radiotherapy. The average delay from creation to closure of the ileostomy was 10.3 mo. Postoperative complications occurred in 40% of the patients, with 1% mortality. The most frequent were ileus (13%) and wound infection (13%). Pseudomembranous colitis appeared in 4%. Increased postoperative complications were associated with delay in ileostomy closure (P = 0.041). Male patients had more complications (P = 0.042), mainly wound infections (P = 0.007). Pseudomembranous colitis was also associated with the delay in ileostomy closure (P = 0.003). End-to-end intestinal anastomosis without resection was significantly associated with postoperative ileus (P = 0.037).

CONCLUSION

Although closure of a protective ileostomy is a fairly common surgical procedure, it has a high rate of complications, and this must be taken into account when the indication is made. The delay in stoma closure can increase the rate of complications in general, and specifically wound infections and colitis.

摘要

目的

研究结直肠手术后回肠造口还纳患者的发病率和相关并发症,以及这些并发症是否与关闭时间有关。

方法

对 2009 年至 2013 年间择期行回肠造口关闭术的 93 例患者进行回顾性分析。回顾分析了患者的人口统计学、临床和手术变量。记录所有并发症,并根据 Clavien-Dindo 分类进行分类。进行了统计学单变量和多变量分析,设定 P 值为 0.05 表示差异有统计学意义。

结果

患者的平均年龄为 60.3 岁,58%为男性。行回肠造口术的主要原因为直肠癌(56%),37%的患者术前接受了放化疗。从造口术到关闭的平均时间为 10.3 个月。40%的患者发生了术后并发症,死亡率为 1%。最常见的并发症为肠梗阻(13%)和伤口感染(13%)。假膜性结肠炎发生率为 4%。术后并发症的增加与回肠造口关闭时间的延迟有关(P=0.041)。男性患者的并发症更多(P=0.042),主要为伤口感染(P=0.007)。假膜性结肠炎也与回肠造口关闭时间的延迟有关(P=0.003)。无切除的端端肠吻合术与术后肠梗阻显著相关(P=0.037)。

结论

尽管保护性回肠造口关闭是一种相当常见的手术,但它的并发症发生率很高,在做出指示时必须考虑到这一点。造口关闭时间的延迟会增加一般并发症的发生率,特别是伤口感染和结肠炎。

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