1 State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China ; 2 The Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
J Thorac Dis. 2014 Sep;6(9):1293-9. doi: 10.3978/j.issn.2072-1439.2014.09.07.
The study aimed to construct and manage an acute respiratory distress syndrome (ARDS)/sepsis registry that can be used for data warehousing and clinical research.
The workflow methodology and software solution of research electronic data capture (REDCap) was used to construct the ARDS/sepsis registry. Clinical data from ARDS and sepsis patients registered to the intensive care unit (ICU) of our hospital formed the registry. These data were converted to the electronic case report form (eCRF) format used in REDCap by trained medical staff. Data validation, quality control, and database management were conducted to ensure data integrity.
The clinical data of 67 patients registered to the ICU between June 2013 and December 2013 were analyzed. Of the 67 patients, 45 (67.2%) were classified as sepsis, 14 (20.9%) as ARDS, and eight (11.9%) as sepsis-associated ARDS. The patients' information, comprising demographic characteristics, medical history, clinical interventions, daily assessment, clinical outcome, and follow-up data, was properly managed and safely stored in the ARDS/sepsis registry. Data efficiency was guaranteed by performing data collection and data entry twice weekly and every two weeks, respectively.
The ARDS/sepsis database that we constructed and manage with REDCap in the ICU can provide a solid foundation for translational research on the clinical data of interest, and a model for development of other medical registries in the future.
本研究旨在构建和管理一个急性呼吸窘迫综合征（ARDS）/脓毒症登记处，用于数据仓库和临床研究。
采用研究电子数据捕获（REDCap）的工作流程方法和软件解决方案来构建 ARDS/脓毒症登记处。我院 ICU 登记的 ARDS 和脓毒症患者的临床数据构成了该登记处。这些数据由经过培训的医务人员转换为 REDCap 中使用的电子病例报告表（eCRF）格式。进行数据验证、质量控制和数据库管理，以确保数据完整性。
对 2013 年 6 月至 12 月期间登记入住 ICU 的 67 名患者的临床数据进行了分析。在这 67 名患者中，45 名（67.2%）被归类为脓毒症，14 名（20.9%）为 ARDS，8 名（11.9%）为脓毒症相关 ARDS。患者的信息，包括人口统计学特征、病史、临床干预、日常评估、临床结果和随访数据，在 ARDS/脓毒症登记处得到妥善管理和安全存储。通过每周两次和每两周分别进行数据收集和数据录入，保证了数据效率。
我们在 ICU 中使用 REDCap 构建和管理的 ARDS/脓毒症数据库可为相关临床数据的转化研究提供坚实的基础，并为未来其他医学登记处的发展提供模型。
