Robbins D R, Alessi N E, Colfer M V
Brown University Program in Medicine, Providence, RI.
J Affect Disord. 1989 Sep-Oct;17(2):99-104. doi: 10.1016/0165-0327(89)90031-1.
Of 38 adolescents hospitalized with major depression, 47% of those receiving psychosocial treatment alone responded. Of the non-responders then treated with combined tricyclic antidepressants and psychosocial treatment, 92% responded. The melancholic subtype and dexamethasone suppression test non-suppression were associated with failure to respond to psychosocial treatment alone. Implications for controlled studies are discussed.
在38名因重度抑郁症住院的青少年中，仅接受心理社会治疗的患者中有47%有反应。在那些无反应者随后接受三环类抗抑郁药与心理社会治疗联合治疗后，92%有反应。抑郁亚型和地塞米松抑制试验无抑制与仅心理社会治疗无反应相关。文中讨论了对对照研究的意义。
