Hokari Masaaki, Isobe Masanori, Asano Takeshi, Itou Yasuhiro, Yamazaki Kazuyoshi, Chiba Yasuhiro, Iwamoto Naotaka, Isu Toyohiko
Department of Neurosurgery, Kushiro Rousai Hospital, Kushiro-shi, Hokkaido, Japan.
Department of Neurosurgery, Kushiro Rousai Hospital, Kushiro-shi, Hokkaido, Japan.
J Stroke Cerebrovasc Dis. 2014 Nov-Dec;23(10):2851-2856. doi: 10.1016/j.jstrokecerebrovasdis.2014.07.014. Epub 2014 Oct 3.
Since the introduction of carotid stenting (CAS), a combined treatment for bilateral lesions using carotid endarterectomy (CEA) and CAS has been developed. However, there has been only 1 report about CEA then CAS. Herein we describe 2 patients with bilateral severe carotid stenosis who were treated by CEA for the symptomatic side and CAS for the contralateral asymptomatic side. A 71-year-old man underwent CEA for the symptomatic side. Although the patient suffered hyperperfusion syndrome after CEA, he recovered fully after 3 weeks of rehabilitation. Two months later, CAS was performed for the asymptomatic side, and he was discharged with no deficit. A 67-year-old man underwent CEA for the symptomatic side. The patient developed no postoperative neurologic deficits except for hoarseness. Four weeks later, CAS was performed for the contralateral asymptomatic side. After the procedure, however, severe hypotension occurred, and treatment by continuous injection of catecholamine was necessary to maintain systematic blood pressure. The patient was ultimately discharged with no deficit. The combined therapy of CAS for the asymptomatic side and then CEA for the symptomatic side has been recommended by several authors. However, one of the problems of this strategy is the higher incidence of postprocedural hemodynamic complications, and hypotension after CAS may be dangerous for the symptomatic hemisphere. We suggest a combined therapy using CEA for the symptomatic side and then CAS for the asymptomatic side can be 1 beneficial treatment option for patients with bilateral carotid stenosis without coronary artery disease.
自从颈动脉支架置入术(CAS)引入以来,一种使用颈动脉内膜切除术(CEA)和CAS联合治疗双侧病变的方法已经得到发展。然而,关于先进行CEA然后进行CAS的报道仅有1例。在此,我们描述2例双侧严重颈动脉狭窄患者,对有症状一侧采用CEA治疗,对侧无症状一侧采用CAS治疗。一名71岁男性对有症状一侧进行了CEA。尽管该患者在CEA后出现了高灌注综合征,但经过3周的康复治疗后完全康复。两个月后,对无症状一侧进行了CAS,他出院时无神经功能缺损。一名67岁男性对有症状一侧进行了CEA。该患者除声音嘶哑外未出现术后神经功能缺损。四周后,对侧无症状一侧进行了CAS。然而,术后出现了严重低血压,需要持续注射儿茶酚胺来维持系统血压。该患者最终出院时无神经功能缺损。几位作者推荐先对无症状一侧进行CAS治疗,然后对有症状一侧进行CEA的联合治疗方法。然而,这种策略的问题之一是术后血流动力学并发症的发生率较高,并且CAS后的低血压对有症状的半球可能是危险的。我们认为,对于无冠状动脉疾病的双侧颈动脉狭窄患者,采用对有症状一侧进行CEA然后对无症状一侧进行CAS的联合治疗可能是一种有益的治疗选择。